학술논문

Simvastatin improves neutrophil function and clinical outcomes in pneumonia: a pilot randomised controlled trial. Online supplement.
Document Type
Article
Source
American Journal of Respiratory & Critical Care Medicine; 11/15/2019, Vol. 200 Issue 10, pE1-E19, 19p
Subject
PNEUMONIA
SIMVASTATIN
FISHER exact test
PLACEBOS
NEUTROPHILS
Language
ISSN
1073449X
Abstract
The article presents a pilot randomised controlled trial for improvement in neutrophil function and clinical outcomes in pneumonia from simvastatin. Topics discussed include information on co-morbidities by organ on an intention to treat basis and compared using Fisher’s Exact test; Simvastatin or placebo as well as standard medical treatment in Patients with pneumonia and sepsis; and NETosis on isolated neutrophils from EDTA vacutainers.