학술논문
Serum IGF-1 Determines Skeletal Strength by Regulating Subperiosteal Expansion and Trait Interactions.
Document Type
Article
Author
Source
Journal of Bone & Mineral Research; Aug2009, Vol. 24 Issue 8, p1481-1492, 12p, 2 Charts, 5 Graphs
Subject
Language
ISSN
08840431
Abstract
The article discusses research on a unique developmental pattern of morphological and compositional traits that contribute to bone strength. It references a study by Shoshana Yakar and colleagues, published on the February 16, 2009 online issue of the "Journal of Bone and Mineral Research." The researches found that impaired subporiosteal expansion combined with impaired endosteal apposition can result from reduced bone strength associated with low levels of insulin-like growth factor-1 (IGF-1) in serum.