학술논문

Nonplatelet Effects of Aspirin During Acute Coronary Occlusion: Electrophysiologic and Cation Alterations in Ischemic Myocardium.
Document Type
Article
Source
Journal of Cardiovascular Pharmacology & Therapeutics; Jun2000, Vol. 5 Issue 2, p113-120, 8p
Subject
ASPIRIN
CORONARY disease
MYOCARDIAL infarction
ISCHEMIA
CATECHOLAMINES
Language
ISSN
10742484
Abstract
The article discusses a study which examined an antiarrhythmic action during sympathetic stimulation in the intact anesthetized dog with and without ischemia. It notes that the therapeutic effects of aspirin (ASA) during acute myocardial infarction have been attributed to an antiplatelet effect. It cites the examination of the ventricular fibrillation threshold (VFT) before and after epinephrine (E) in normals (group I). The study concluded that ASA antagonizes the reduction of the VFT induced by catecholamine in normals.