학술논문
Moving the Dial on Airway Inflammation in Response to Trikafta in Adolescents with Cystic Fibrosis.
Document Type
Article
Author
Source
American Journal of Respiratory & Critical Care Medicine; 3/15/2023, Vol. 207 Issue 6, p792-795, 4p
Subject
Language
ISSN
1073449X
Abstract
The article presents a study on the short-term effect of elexacaftor, tezacaftor, and ivacaftor (ETI) on lung inflammation in adolescents with cystic fibrosis (CF). Results show a decrease in sputum and blood inflammatory markers at 1 month after ETI initiation, and contradictory reports on the effect of highly effective modulator therapy (HEMT) on inflammation. Also noted is the suggestion that HEMT may prevent or at least attenuate longer-term pulmonary decline.