학술논문
Inhaled Iloprost Improves Right Ventricular Load-Independent Contractility in Pulmonary Hypertension.
Document Type
letter
Author
Source
American Journal of Respiratory & Critical Care Medicine; 7/1/2022, Vol. 206 Issue 1, p111-114, 4p
Subject
Language
ISSN
1073449X
Abstract
The article reports that parenteral prostacyclins are recommended for the treatment of severe pulmonary arterial hypertension (PAH) with efficacy related to positive inotropic effects on the right ventricle (RV). It mentions about early in vitro studies drug-induced decrease in afterload arterial elastance accompanied by paradoxical decrease in contractility end-systolic elastance preserving RV–pulmonary arterial coupling.