학술논문

Plasma metabolomics reveals distinct biological and diagnostic signatures for melioidosis.
Document Type
Article
Source
American Journal of Respiratory & Critical Care Medicine; 2/1/2024, Vol. 209 Issue 3, pE1-E22, 22p
Subject
MELIOIDOSIS
PROTON magnetic resonance spectroscopy
METABOLOMICS
COMMUNITY-acquired infections
AMINO acid metabolism
Language
ISSN
1073449X
Abstract
The article focuses on determining the etiology of infection in patients from the Ubon-Sepsis study, categorizing bacteremias and non-bacteremic cases of melioidosis, along with identifying culture-negative cases. Topics include the methodology of metabolomics analysis conducted by Metabolon, Inc., involving sample preparation, chromatography, mass spectrometry, and quality control procedures to analyze plasma samples obtained from study participants.