학술논문

Reduced Progenitor Function and Altered Immune Landscape Contribute to Field Cancerization of Lung Adenocarcinoma.
Document Type
Article
Source
American Journal of Respiratory & Critical Care Medicine; 10/15/2023, Vol. 208 Issue 8, p903-905, 3p
Subject
ADENOCARCINOMA
LUNGS
Language
ISSN
1073449X
Abstract
The article focuses on field cancerization in lung adenocarcinoma (ADC) and the early changes associated with or permissive of cancer development in the peripheral lung. Topics discussed include reduced progenitor cell function, altered immune responses, and the accumulation of cancer-associated mutations in the contralateral lungs of individuals with early-stage ADC identified through screening chest CT.