학술논문
Results of phenol red thread test in clinically normal Syrian hamsters (Mesocricetus auratus).
Document Type
Academic Journal
Author
Rajaei SM; Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.; Sadjadi R; Sabzevari A; Ghaffari MS
Source
Publisher: Blackwell Science Country of Publication: England NLM ID: 100887377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-5224 (Electronic) Linking ISSN: 14635216 NLM ISO Abbreviation: Vet Ophthalmol Subsets: MEDLINE
Subject
Language
English
Abstract
Objective: To determine the normal reference range for phenol red thread test (PRTT) values in clinically normal Syrian hamsters (Mesocricetus auratus).
Animals: Sixteen healthy adult Syrian hamsters (eight males and eight females) were used in this study.
Procedure: Ophthalmic examinations were performed without chemical restraint. PRTT values were evaluated in both eyes of all Syrian hamsters using a commercial PRTT strip of a single lot number.
Results: No statistically significant differences between right and left eyes were found for any of the results. The mean ± SD PRTT values for the study population were 6.8 ± 2.5 mm/15 s with a range from 3 to 11.5 mm/15 s. Mean PRTTs in male animals were 5.1 ± 1.2 mm/15 s, whereas mean PRTTs in female hamsters were 8.5 ± 2.3 mm/15 s. Comparison between mean PRTT values in males and females showed a significant difference (P = 0.004). Mean weights for males and females were 80.9 ± 4.8 and 90.6 ± 8.5 g, respectively. No linear relationship between mean PRTT and body weight was found in female (P = 0.46) and male (P = 0.92) hamsters.
Conclusion: This study provides novel data for normal reference ranges of PRTT values in healthy Syrian hamsters. Results of this study may assist veterinarians in the diagnosis of ocular surface disease and syndromes affecting the tear film in these species.
(© 2013 American College of Veterinary Ophthalmologists.)
Animals: Sixteen healthy adult Syrian hamsters (eight males and eight females) were used in this study.
Procedure: Ophthalmic examinations were performed without chemical restraint. PRTT values were evaluated in both eyes of all Syrian hamsters using a commercial PRTT strip of a single lot number.
Results: No statistically significant differences between right and left eyes were found for any of the results. The mean ± SD PRTT values for the study population were 6.8 ± 2.5 mm/15 s with a range from 3 to 11.5 mm/15 s. Mean PRTTs in male animals were 5.1 ± 1.2 mm/15 s, whereas mean PRTTs in female hamsters were 8.5 ± 2.3 mm/15 s. Comparison between mean PRTT values in males and females showed a significant difference (P = 0.004). Mean weights for males and females were 80.9 ± 4.8 and 90.6 ± 8.5 g, respectively. No linear relationship between mean PRTT and body weight was found in female (P = 0.46) and male (P = 0.92) hamsters.
Conclusion: This study provides novel data for normal reference ranges of PRTT values in healthy Syrian hamsters. Results of this study may assist veterinarians in the diagnosis of ocular surface disease and syndromes affecting the tear film in these species.
(© 2013 American College of Veterinary Ophthalmologists.)