학술논문
Thrombocytopenia: the most frequent haemostatic disorder in the ICU.
Document Type
Academic Journal
Author
Pluta J; I Klinika Anestezjologii i Intensywnej Terapii, Warszawski Uniwersytet Medyczny. jan.pluta@wum.edu.pl.; Trzebicki J; I Klinika Anestezjologii i Intensywnej Terapii, Warszawski Uniwersytet Medyczny.
Source
Publisher: Termedia sp. z.o.o Country of Publication: Poland NLM ID: 101472620 Publication Model: Print Cited Medium: Internet ISSN: 1731-2531 (Electronic) Linking ISSN: 16425758 NLM ISO Abbreviation: Anaesthesiol Intensive Ther Subsets: MEDLINE
Subject
Language
English
Abstract
Thrombocytopenia is the most common haemostatic disorder in patients admitted to Intensive Care Units (ICUs). The mechanisms contributing to a decrease in the platelet count in critically ill patients are multifactorial, among which sepsis and trauma are the most frequent. A differential diagnosis of profound thrombocytopenia is crucial for effective treatment. A low platelet count is a strong independent predictor of morbidity and mortality because it is associated with life-threatening bleeding or thrombosis. This article aims to outline the definition and pathophysiology of thrombocytopenia and present a three-step algorithm of the clinical management of this haemostatic disorder.