학술논문
[Necessity to define thyroid reference values for better clinical interpretation].
Document Type
Academic Journal
Author
Plouvier E; Laboratoire de biochimie, Centre hospitalier, Meaux. e-plouvier@ch-meaux.fr; Alliot L; Bigorie B; Kowalski C; Medeau V; Thuillier F
Source
Publisher: John Libbey Eurotext Country of Publication: France NLM ID: 2984690R Publication Model: Print Cited Medium: Print ISSN: 0003-3898 (Print) Linking ISSN: 00033898 NLM ISO Abbreviation: Ann Biol Clin (Paris) Subsets: MEDLINE
Subject
Language
French
ISSN
0003-3898
Abstract
Discordances were observed with thyroid reference range from BCF Access 2 analyser. The purpose of this study was to establish specific reference range value for free thyroxine (FT4), free triiodothyronine (FT3) and thyrotropin (TSH) in adult Meaux Hospital population. Samples from 308 adults aged from 18 to 65 years were studied. Patients (no pregnancy and no iodine contrast media used) after informed consent, were exempted of thyroidal, cardiac, renal, multiple-organ-failure illnesses. Thyroid assays, anti-TPO and anti-TG levels were measured on the BCF Access2 immunoassay system. This work exposes difficulties to define range values in order to better use the biomarker in the clinical context.