학술논문
Clinical role of breast MRI now and going forward.
Document Type
Academic Journal
Author
Leithner D; University Hospital Frankfurt, Department of Diagnostic and Interventional Radiology, Frankfurt, Germany; Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria.; Wengert GJ; Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria.; Helbich TH; Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria.; Thakur S; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Ochoa-Albiztegui RE; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Morris EA; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Pinker K; Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: pinkerdk@mskcc.org.
Source
Publisher: Blackwell Scientific Publications Ltd Country of Publication: England NLM ID: 1306016 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-229X (Electronic) Linking ISSN: 00099260 NLM ISO Abbreviation: Clin Radiol Subsets: MEDLINE
Subject
Language
English
Abstract
Magnetic resonance imaging (MRI) is a well-established method in breast imaging, with manifold clinical applications, including the non-invasive differentiation between benign and malignant breast lesions, preoperative staging, detection of scar versus recurrence, implant assessment, and the evaluation of high-risk patients. At present, dynamic contrast-enhanced MRI is the most sensitive imaging technique for breast cancer diagnosis, and provides excellent morphological and to some extent also functional information. To compensate for the limited functional information, and to increase the specificity of MRI while preserving its sensitivity, additional functional parameters such as diffusion-weighted imaging and apparent diffusion coefficient mapping, and MR spectroscopic imaging have been investigated and implemented into the clinical routine. Several additional MRI parameters to capture breast cancer biology are still under investigation. MRI at high and ultra-high field strength and advances in hard- and software may also further improve this imaging technique. This article will review the current clinical role of breast MRI, including multiparametric MRI and abbreviated protocols, and provide an outlook on the future of this technique. In addition, the predictive and prognostic value of MRI as well as the evolving field of radiogenomics will be discussed.
(Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.)
(Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.)