학술논문
Management of Severe Atopic Dermatitis in Pediatric Patients.
Document Type
Academic Journal
Author
Mancuso JB; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Mich.; Lee SS; Departments of Dermatology and Pediatrics, University of California San Diego, San Diego, Calif; Pediatric and Adolescent Dermatology, Rady Children's Hospital San Diego, San Diego, Calif.; Paller AS; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Ill.; Ohya Y; Allergy Center, National Center for Child Health and Development, Tokyo, Japan.; Eichenfield LF; Departments of Dermatology and Pediatrics, University of California San Diego, San Diego, Calif; Pediatric and Adolescent Dermatology, Rady Children's Hospital San Diego, San Diego, Calif. Electronic address: leichenfield@rchsd.org.
Source
Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101597220 Publication Model: Print Cited Medium: Internet ISSN: 2213-2201 (Electronic) NLM ISO Abbreviation: J Allergy Clin Immunol Pract Subsets: MEDLINE
Subject
Language
English
Abstract
Atopic dermatitis is a common, chronic inflammatory skin disorder, present in about 12% of children worldwide. Optimizing management of severe atopic dermatitis in pediatric patients is critical to reduce signs of inflammation, alleviate pruritus and sleep disturbance, minimize the development and/or impact of comorbidities, and improve the patient and caregiver's quality of life. Evaluating the longitudinal severity of pediatric atopic dermatitis is an important component of measuring therapeutic response and long-term management, and is different in clinical practice versus clinical trials. This article describes when and how to use different treatments for pediatric patients with severe atopic dermatitis, including topical medications, phototherapy, and systemic medical therapies (traditional immunosuppressants, biologics, and small molecule inhibitors). It also provides recommendations useful in clinical practice for nonpharmacologic interventions for pediatric patients with severe atopic dermatitis.
(Copyright © 2021. Published by Elsevier Inc.)
(Copyright © 2021. Published by Elsevier Inc.)