학술논문
Advance care planning and end-of-life decision making in dialysis: a randomized controlled trial targeting patients and their surrogates.
Document Type
Academic Journal
Author
Song MK; School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address: songm@email.unc.edu.; Ward SE; School of Nursing, University of Wisconsin-Madison, Madison, WI.; Fine JP; School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.; Hanson LC; School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.; Lin FC; School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.; Hladik GA; University of North Carolina Kidney Center, Chapel Hill, NC.; Hamilton JB; School of Nursing, Johns Hopkins University, Baltimore, MD.; Bridgman JC; School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Source
Publisher: W.B. Saunders Country of Publication: United States NLM ID: 8110075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-6838 (Electronic) Linking ISSN: 02726386 NLM ISO Abbreviation: Am J Kidney Dis Subsets: MEDLINE
Subject
Language
English
Abstract
Background: Few trials have examined long-term outcomes of advance care planning (ACP) interventions. We examined the efficacy of an ACP intervention on preparation for end-of-life decision making for dialysis patients and surrogates and for surrogates' bereavement outcomes.
Study Design: A randomized trial compared an ACP intervention (Sharing Patient's Illness Representations to Increase Trust [SPIRIT]) to usual care alone, with blinded outcome assessments.
Setting & Participants: 420 participants (210 dyads of prevalent dialysis patients and their surrogates) from 20 dialysis centers.
Intervention: Every dyad received usual care. Those randomly assigned to SPIRIT had an in-depth ACP discussion at the center and a follow-up session at home 2 weeks later.
Primary Outcomes: preparation for end-of-life decision making, assessed for 12 months, included dyad congruence on goals of care at end of life, patient decisional conflict, surrogate decision-making confidence, and a composite of congruence and surrogate decision-making confidence.
Secondary Outcomes: bereavement outcomes, assessed for 6 months, included anxiety, depression, and posttraumatic distress symptoms completed by surrogates after patient death.
Primary Outcomes: adjusting for time and baseline values, dyad congruence (OR, 1.89; 95% CI, 1.1-3.3), surrogate decision-making confidence (β=0.13; 95% CI, 0.01-0.24), and the composite (OR, 1.82; 95% CI, 1.0-3.2) were better in SPIRIT than controls, but patient decisional conflict did not differ between groups (β=-0.01; 95% CI, -0.12 to 0.10).
Secondary Outcomes: 45 patients died during the study. Surrogates in SPIRIT had less anxiety (β=-1.13; 95% CI, -2.23 to -0.03), depression (β=-2.54; 95% CI, -4.34 to -0.74), and posttraumatic distress (β=-5.75; 95% CI, -10.9 to -0.64) than controls.
Limitations: Study was conducted in a single US region.
Conclusions: SPIRIT was associated with improvements in dyad preparation for end-of-life decision making and surrogate bereavement outcomes.
(Copyright © 2015 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.)
Study Design: A randomized trial compared an ACP intervention (Sharing Patient's Illness Representations to Increase Trust [SPIRIT]) to usual care alone, with blinded outcome assessments.
Setting & Participants: 420 participants (210 dyads of prevalent dialysis patients and their surrogates) from 20 dialysis centers.
Intervention: Every dyad received usual care. Those randomly assigned to SPIRIT had an in-depth ACP discussion at the center and a follow-up session at home 2 weeks later.
Primary Outcomes: preparation for end-of-life decision making, assessed for 12 months, included dyad congruence on goals of care at end of life, patient decisional conflict, surrogate decision-making confidence, and a composite of congruence and surrogate decision-making confidence.
Secondary Outcomes: bereavement outcomes, assessed for 6 months, included anxiety, depression, and posttraumatic distress symptoms completed by surrogates after patient death.
Primary Outcomes: adjusting for time and baseline values, dyad congruence (OR, 1.89; 95% CI, 1.1-3.3), surrogate decision-making confidence (β=0.13; 95% CI, 0.01-0.24), and the composite (OR, 1.82; 95% CI, 1.0-3.2) were better in SPIRIT than controls, but patient decisional conflict did not differ between groups (β=-0.01; 95% CI, -0.12 to 0.10).
Secondary Outcomes: 45 patients died during the study. Surrogates in SPIRIT had less anxiety (β=-1.13; 95% CI, -2.23 to -0.03), depression (β=-2.54; 95% CI, -4.34 to -0.74), and posttraumatic distress (β=-5.75; 95% CI, -10.9 to -0.64) than controls.
Limitations: Study was conducted in a single US region.
Conclusions: SPIRIT was associated with improvements in dyad preparation for end-of-life decision making and surrogate bereavement outcomes.
(Copyright © 2015 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.)