학술논문
The prognostic, diagnostic, and therapeutic impact of Long noncoding RNAs in gastric cancer.
Document Type
Academic Journal
Author
Ghorbani A; Department of Biology, East Tehran Branch, Islamic Azad University, Tehran, Iran.; Hosseinie F; Department of Nursing, Faculty of Nursing and Midwifery, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran.; Khorshid Sokhangouy S; Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.; Islampanah M; Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.; Khojasteh-Leylakoohi F; Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.; Maftooh M; Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.; Nassiri M; Recombinant Proteins Research Group, The Research Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran.; Hassanian SM; Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Basic Sciences Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Ghayour-Mobarhan M; Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Basic Sciences Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Ferns GA; Division of Medical Education, Brighton & Sussex Medical School, Falmer, Brighton, Sussex BN1 9PH, UK.; Khazaei M; Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Basic Sciences Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Nazari E; Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: Elham.Nazari@sbmu.ac.ir.; Avan A; Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Basic Sciences Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: avana@mums.ac.ir.
Source
Publisher: Elsevier Country of Publication: United States NLM ID: 101539150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2210-7762 (Print) NLM ISO Abbreviation: Cancer Genet Subsets: MEDLINE
Subject
Language
English
ISSN
2210-7762
Abstract
Gastric cancer (GC), ranking as the third deadliest cancer globally, faces challenges of late diagnosis and limited treatment efficacy. Long non-coding RNAs (lncRNAs) emerge as valuable treasured targets for cancer prognosis, diagnosis, and therapy, given their high specificity, convenient non-invasive detection in body fluids, and crucial roles in diverse physiological and pathological processes. Research indicates the significant involvement of lncRNAs in various aspects of GC pathogenesis, including initiation, metastasis, and recurrence, underscoring their potential as novel diagnostic and prognostic biomarkers, as well as therapeutic targets for GC. Despite existing challenges in the clinical application of lncRNAs in GC, the evolving landscape of lncRNA molecular biology holds promise for advancing the survival and treatment outcomes of gastric cancer patients. This review provides insights into recent studies on lncRNAs in gastric cancer, elucidating their molecular mechanisms and exploring the potential clinical applications in GC.
Competing Interests: Declaration of Competing Interest I hereby confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome
(Crown Copyright © 2023. Published by Elsevier Inc. All rights reserved.)
Competing Interests: Declaration of Competing Interest I hereby confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome
(Crown Copyright © 2023. Published by Elsevier Inc. All rights reserved.)