학술논문
Development and Validation of the Short Version of the Reflux Symptom Score: Reflux Symptom Score-12.
Document Type
Academic Journal
Author
Lechien JR; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Department of Human Anatomy and Experimental Oncology, School of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium.; Department of Otorhinolaryngology-Head and Neck Surgery, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.; Department of Otolaryngology-Head and Neck Surgery, Foch Hospital (University of Paris-Saclay), Paris, France.; Bobin F; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Department of Otorhinolaryngology-Head and Neck Surgery, Polyclinique Elsan de Poitiers, Poitiers, France.; Rodriguez A; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Department of Otorhinolaryngology-Head and Neck Surgery, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.; Dequanter D; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Department of Otorhinolaryngology-Head and Neck Surgery, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.; Muls V; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Department of Gastroenterology and Endoscopy, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.; Huet K; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Laboratory of Phonetics, Faculty of Psychology, Research Institute for Language Sciences and Technology, University of Mons, Mons, Belgium.; Harmegnies B; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Laboratory of Phonetics, Faculty of Psychology, Research Institute for Language Sciences and Technology, University of Mons, Mons, Belgium.; Crevier-Buchman L; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Department of Otolaryngology-Head and Neck Surgery, Foch Hospital (University of Paris-Saclay), Paris, France.; Hans S; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Department of Otolaryngology-Head and Neck Surgery, Foch Hospital (University of Paris-Saclay), Paris, France.; Saussez S; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Department of Human Anatomy and Experimental Oncology, School of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium.; Department of Otorhinolaryngology-Head and Neck Surgery, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.; Carroll TL; Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School; Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Source
Publisher: Wiley Country of Publication: England NLM ID: 8508176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6817 (Electronic) Linking ISSN: 01945998 NLM ISO Abbreviation: Otolaryngol Head Neck Surg Subsets: MEDLINE
Subject
Language
English
Abstract
Objective: To develop and validate a short version of the Reflux Symptom Score-the 12-question Reflux Symptom Score-12 (RSS-12)-for patients with laryngopharyngeal reflux disease (LPR).
Study Design: Prospective study.
Setting: Multicenter academic hospitals.
Methods: Patients with LPR diagnosed via multichannel intraluminal impedance pH monitoring were enrolled from 3 European hospitals. Healthy individuals completed the study. Individuals completed the Reflux Symptom Score, Reflux Symptom Index (RSI), and Voice Handicap Index (VHI) at baseline and 3 months posttreatment. The Reflux Symptom Score was completed twice within a 7-day period to assess test-retest reliability. Cronbach's α was used for assessing internal consistency. The RSS-12 was developed and validity assessed through a comparison of the RSS-12, RSI, and VHI. Responsiveness to change was evaluated through the pre- to posttreatment evolution of the RSS-12 total score. Receiver operating characteristic analysis was used to determine the RSS-12 threshold that is suggestive of LPR.
Results: The RSS-12 was characterized by high test-retest reliability ( rs = 0.956) and adequate internal consistency reliability (α = 0.739). The RSS-12 was significantly correlated with the RSI ( r s = 0.845), suggesting high external validity. The RSS-12 total and item scores were significantly higher in patients with LPR as compared with healthy individuals ( P = .001), supporting high internal validity. RSS-12, VHI, and RSI significantly improved throughout treatment. Regarding the receiver operating characteristic curve, an RSS-12 score >11 is suggestive of LPR, exhibiting a sensitivity of 94.5% and a specificity of 86.2%.
Conclusion: The RSS-12 is a shorter, reliable, and valid self-administered patient-reported outcome measure questionnaire that can be used in the outpatient setting to suggest and monitor LPR.
Study Design: Prospective study.
Setting: Multicenter academic hospitals.
Methods: Patients with LPR diagnosed via multichannel intraluminal impedance pH monitoring were enrolled from 3 European hospitals. Healthy individuals completed the study. Individuals completed the Reflux Symptom Score, Reflux Symptom Index (RSI), and Voice Handicap Index (VHI) at baseline and 3 months posttreatment. The Reflux Symptom Score was completed twice within a 7-day period to assess test-retest reliability. Cronbach's α was used for assessing internal consistency. The RSS-12 was developed and validity assessed through a comparison of the RSS-12, RSI, and VHI. Responsiveness to change was evaluated through the pre- to posttreatment evolution of the RSS-12 total score. Receiver operating characteristic analysis was used to determine the RSS-12 threshold that is suggestive of LPR.
Results: The RSS-12 was characterized by high test-retest reliability ( r
Conclusion: The RSS-12 is a shorter, reliable, and valid self-administered patient-reported outcome measure questionnaire that can be used in the outpatient setting to suggest and monitor LPR.