학술논문
Preoperative medications is one of the factor affecting patient-reported outcomes after total hip arthroplasty.
Document Type
Academic Journal
Author
Miura T; Department of Orthopedic Surgery, Kakunodate General Hospital, 3 Iwase, Kakunodate, Senboku, Akita, 014-0394, Japan.; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Kijima H; Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita, 010-8543, Japan.; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Konishi N; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Kubota H; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Yamada S; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Tazawa H; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Tani T; Department of Orthopedic Surgery, Kakunodate General Hospital, 3 Iwase, Kakunodate, Senboku, Akita, 014-0394, Japan.; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Suzuki N; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Kamo K; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Fujii M; Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita, 010-8543, Japan.; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Sasaki K; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Kawano T; Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita, 010-8543, Japan.; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Iwamoto Y; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Nagahata I; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.; Miyakoshi N; Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita, 010-8543, Japan.; Shimada Y; Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita, 010-8543, Japan.; Akita Hip Research Group (AHRG), 1-1-1 Hondo, Akita, 010-8543, Japan.
Source
Publisher: COAA Country of Publication: India NLM ID: 101233220 Publication Model: eCollection Cited Medium: Print ISSN: 0972-978X (Print) Linking ISSN: 0972978X NLM ISO Abbreviation: J Orthop Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
0972-978X
Abstract
Although the reported clinical outcomes of total hip arthroplasty (THA) for hip osteoarthritis are satisfactory, not all patients are completely satisfied. Thus, there is interest in predicting postoperative satisfaction before surgery. The influence of comorbidities and preoperative medications on the incidence of complications and duration of hospitalization following THA has become apparent. However, studies about the associations of preoperative medication with clinical outcomes of THA are limited. Therefore, this study aimed to clarify the relationship between preoperative medications and postoperative patient-reported outcomes. This retrospective cross-sectional multicenter study enrolled post-THA patients (79 patients, 90 hips) who were examined from February to March 2019 in eight general hospitals. Outcome measures included patient-reported outcome as Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire (JHEQ) score. Preoperative medications were investigated from medical records. Medications were categorized, and analgesics were categorized into non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, pregabalin, duloxetine, neurotropin (an extract from inflammatory rabbit skin inoculated by vaccinia virus), and opioid. To identify the factors associated with JHEQ score, the patients were divided into lower (<55 score) and higher (≥55) JHEQ score groups. Spearman rank correlation coefficient (r) showed significant difference between the total number of preoperative medications and postoperative JHEQ movement subscale (r = -0.37, p < 0.01), mental subscale (r = -0.29, p < 0.01), and JHEQ (r = -0.30, p < 0.01) scores. In the multiple logistic regression analysis, only the total number of preoperative medications was identified as a risk factor for lower JHEQ score (p < 0.01). This study clarified an inverse correlation between the total preoperative medication count and postoperative outcomes and found that larger total count of preoperative medications is a risk factor of poor postoperative patient-reported outcomes of THA.
Competing Interests: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
(© 2020 Published by Elsevier B.V. on behalf of Professor P K Surendran Memorial Education Foundation.)
Competing Interests: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
(© 2020 Published by Elsevier B.V. on behalf of Professor P K Surendran Memorial Education Foundation.)