학술논문

Lung nodule and functional changes in smokers after smoking cessation short-term treatment.
Document Type
Academic Journal
Author
Maci E; Department of Medical Oncology, University Campus Bio-Medico , Rome,1,2.; Comito FFrezza AMTonini GPezzuto A
Source
Publisher: Taylor & Francis Country of Publication: England NLM ID: 8307154 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-4192 (Electronic) Linking ISSN: 07357907 NLM ISO Abbreviation: Cancer Invest Subsets: MEDLINE
Subject
Language
English
Abstract
Background: Tobacco smoke causes lung disfunction and inflammation.
Methods: Twenty-two consecutive smokers with undetermined lung nodules were included. All underwent a baseline imaging, exhaled carbon monoxide level evaluation and spirometry, repeated at three months from smoking cessation therapy.
Results: A significant reduction in size of the lung nodules was reported (p = .037) as a trend in number reduction (p = .11). A significant increase in blood arterial oxygen pressure (p < .0001), heart rate reduction (p < .01), and FEV1 increase (p < .0001) was recorded.
Conclusions: Smoking cessation reduces number and size of lung nodules and improves in lung functionality.