학술논문
[Radioimmunotherapy in patients with ovarian cancer in complete remission after the first line surgery and chemotherapy after second look laparoscopy procedure].
Document Type
Academic Journal
Author
Markowska J; Katedry Onkologii AM w Poznaniu.; Madry R; Kierzkowski J; Malicki J; Roszak A; Lubin J; Bratos K
Source
Publisher: Via Medica Journals Country of Publication: Poland NLM ID: 0374641 Publication Model: Print Cited Medium: Print ISSN: 0017-0011 (Print) Linking ISSN: 00170011 NLM ISO Abbreviation: Ginekol Pol Subsets: MEDLINE
Subject
Language
Polish
ISSN
0017-0011
Abstract
Objectives: The aim of the study was analysed a chance to successful radioimmunotherapy in patients with ovarian cancer as a consolidation procedure.
Design: Between 2000 and 2002 we introduced 56 patients into consolidation study with radioimmunotherapy after second look laparoscopy.
Materials and Methods: 17 patients during screening procedure have failed--mostly with positive CT scans (9/17). We have done 39 laparoscopies. Among 11 patients during laparoscopy we have found in 6 cases a residual disease and in 5 cases adhesions in abdomen or pelvis and this group was excluded from study. The remaining 28 patients were divided into two groups--14 in active and 14 in control arm.
Results: Only 50% of patients with ovarian cancer in complete clinical remission after first line surgery and chemotherapy can be candidates to consolidation therapy. Among patients subjected to laparoscopy in 70% there was no evidence of macroscopic disease and adhesions.
Conclusions: Only 50% patients in complete clinical remission after first line surgery and chemotherapy have chance to successful radioimmunotherapy.
Design: Between 2000 and 2002 we introduced 56 patients into consolidation study with radioimmunotherapy after second look laparoscopy.
Materials and Methods: 17 patients during screening procedure have failed--mostly with positive CT scans (9/17). We have done 39 laparoscopies. Among 11 patients during laparoscopy we have found in 6 cases a residual disease and in 5 cases adhesions in abdomen or pelvis and this group was excluded from study. The remaining 28 patients were divided into two groups--14 in active and 14 in control arm.
Results: Only 50% of patients with ovarian cancer in complete clinical remission after first line surgery and chemotherapy can be candidates to consolidation therapy. Among patients subjected to laparoscopy in 70% there was no evidence of macroscopic disease and adhesions.
Conclusions: Only 50% patients in complete clinical remission after first line surgery and chemotherapy have chance to successful radioimmunotherapy.