학술논문
Use of high-resolution volumetric MR spectroscopic imaging in assessing treatment response of glioblastoma to an HDAC inhibitor.
Document Type
Academic Journal
Author
Source
Publisher: American Roentgen Ray Society Country of Publication: United States NLM ID: 7708173 Publication Model: Print Cited Medium: Internet ISSN: 1546-3141 (Electronic) Linking ISSN: 0361803X NLM ISO Abbreviation: AJR Am J Roentgenol Subsets: MEDLINE
Subject
Language
English
Abstract
Objective: Improved predictive imaging would enable personalization and adjustment of treatment, which are critical for patients with glioblastomain whom therapy is likely to fail. This article describes the use of MR spectroscopic imaging (MRSI) to predict early clinical and behavioral response to a therapy and an effort to develop high-resolution, volumetric MRSI to improve its clinical application.
Conclusion: MRSI may enable quantitative analysis of brain tumor response, offering a precise tool for monitoring of patients in clinical trials.
Conclusion: MRSI may enable quantitative analysis of brain tumor response, offering a precise tool for monitoring of patients in clinical trials.