학술논문
Combined pesticides in field doses weaken honey bee (Apis cerana F.) flight ability and analyses of transcriptomics and metabolomics.
Document Type
Academic Journal
Author
Ma C; Longping Branch Graduate School, College of Biology, Hunan University, Changsha 410125, China; Key laboratory of Pesticide Assessment, Ministry of Agriculture and Rural Affairs, Hunan Academy of Agricultural Sciences, Changsha 410125, China.; Shi X; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Chen S; University of Liverpool, Department of Earth, Ocean and Ecological Sciences, School of Environmental Sciences, Liverpool L69 3BX, UK; Department of Health and Environmental Sciences, Xi'an-Jiaotong Liverpool University, Suzhou 215123, China.; Han J; Longping Branch Graduate School, College of Biology, Hunan University, Changsha 410125, China; Key laboratory of Pesticide Assessment, Ministry of Agriculture and Rural Affairs, Hunan Academy of Agricultural Sciences, Changsha 410125, China.; Bai H; Key laboratory of Pesticide Assessment, Ministry of Agriculture and Rural Affairs, Hunan Academy of Agricultural Sciences, Changsha 410125, China.; Li Z; Key laboratory of Pesticide Assessment, Ministry of Agriculture and Rural Affairs, Hunan Academy of Agricultural Sciences, Changsha 410125, China. Electronic address: lizuren88214@hunaas.cn.; Li-Byarlay H; Agriculture Research and Development Program, Central State University, Wilberforce OH, 45384, USA. Electronic address: hli-byarlay@centralstate.edu.; Bai L; Longping Branch Graduate School, College of Biology, Hunan University, Changsha 410125, China; Key laboratory of Pesticide Assessment, Ministry of Agriculture and Rural Affairs, Hunan Academy of Agricultural Sciences, Changsha 410125, China. Electronic address: lybai@hunaas.cn.
Source
Publisher: Academic Press Country of Publication: United States NLM ID: 1301573 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9939 (Electronic) Linking ISSN: 00483575 NLM ISO Abbreviation: Pestic Biochem Physiol Subsets: MEDLINE
Subject
Language
English
Abstract
Imidacloprid, chlorpyrifos, and glyphosate rank among the most extensively employed pesticides worldwide. The effects of these pesticides and their combined on the flight capability of Apis cerana, and the potential underlying mechanisms remain uncertain. To investigate these effects, we carried out flight mill, transcriptome, and metabolome experiments. Our findings reveal that individual acute oral treatments with pesticides, specifically 20 μL of 10 ng/g imidacloprid (0.2 ng per bee), 30 ng/g chlorpyrifos (0.6 ng per bee), and 60 ng/g glyphosate (1.2 ng per bee), did not impact the flight capability of the bees. However, when bees were exposed to a combination of two or three pesticides, a notable reduction in flight duration and distance was observed. In the transcriptomic and metabolomic analyses, we identified 307 transcripts and 17 metabolites that exhibited differential expression following exposure to combined pesticides, primarily associated with metabolic pathways involved in energy regulation. Our results illuminate the intricate effects and potential hazards posed by combined pesticide exposures on bee behavior. These findings offer valuable insights into the synergistic potential of pesticide combinations and their capacity to impair bee behavior. Understanding these complex interactions is essential for comprehending the broader consequences of pesticide formulations on honey bee populations.
Competing Interests: Declaration of competing interest The authors declare no competing financial interests.
(Copyright © 2024. Published by Elsevier Inc.)
Competing Interests: Declaration of competing interest The authors declare no competing financial interests.
(Copyright © 2024. Published by Elsevier Inc.)