학술논문

Postoperative Ovarian Vein Thrombosis and Treatment with Direct Oral Anticoagulant.
Document Type
Report
Author
Shukr G; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA.; Gonte MR; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA.; Department of Medicine, Wayne State University School of Medicine, Detroit, Michigan, USA.; Department of Global Health and Population, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.; Webber VE; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA.; Department of Medicine, Wayne State University School of Medicine, Detroit, Michigan, USA.; Abood JA; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA.; Arsanious S; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA.; Eisenstein D; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA.
Source
Publisher: Wolters Kluwer - Medknow Country of Publication: India NLM ID: 101604085 Publication Model: eCollection Cited Medium: Print ISSN: 2213-3070 (Print) Linking ISSN: 22133070 NLM ISO Abbreviation: Gynecol Minim Invasive Ther Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2213-3070
Abstract
Postoperative ovarian vein thrombosis (OVT) is a rare complication following hysterectomy. Due to its ambiguous presentation, most frequently presenting as a fever with no known source and lower quadrant abdominal pain, OVTs are commonly diagnosed incidentally on computed tomography as a low-attenuation thrombus in place of the ovarian vein. The cornerstones of OVT treatment include anticoagulation and antibiotic therapy; however, there are no current guidelines to inform provider decision-making regarding specific anticoagulant agents, dosing, or length of therapy. We present a patient with a history of deep-vein thrombosis, who presented to the emergency department with OVT following a laparoscopic hysterectomy. She was treated with apixaban, a direct oral anticoagulant (DOAC), and experienced repeated episodes of vaginal bleeding and hematoma expansion. We present this case to instill a high index of suspicion for OVT after laparoscopic hysterectomy, and to discuss the role of DOACs in patients with thromboembolic disease and concurrent bleeding.
Competing Interests: There are no conflicts of interest.
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