학술논문
Barriers and facilitators to hepatitis B birth dose vaccination: Perspectives from healthcare providers and pregnant women accessing antenatal care in Nigeria.
Document Type
Academic Journal
Author
Freeland C; Hepatitis B Foundation, Doylestown, Pennsylvania, United States of America.; Kanu F; Global Immunization Division, United States, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.; Mohammed Y; Department of Medical Microbiology and Parasitology, College of Health Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria.; African Field Epidemiology Network, Abuja, Nigeria.; Nwokoro UU; African Field Epidemiology Network, Abuja, Nigeria.; Department of Community Medicine, University of Nigeria Teaching Hospital, Enugu, Nigeria.; Sandhu H; Global Immunization Division, United States, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.; Ikwe H; Global Immunization Division, United States, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.; Centers for Disease Control and Prevention Nigeria, Abuja, Nigeria.; Uba B; African Field Epidemiology Network, Abuja, Nigeria.; National Emergency Routine Immunization Coordination Centre, Abuja, Nigeria.; Asekun A; Global Immunization Division, United States, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.; Centers for Disease Control and Prevention Nigeria, Abuja, Nigeria.; Akataobi C; African Field Epidemiology Network, Abuja, Nigeria.; National Stop Transmission of Poliomyelitis, Abuja, Nigeria.; Adewole A; African Field Epidemiology Network, Abuja, Nigeria.; National Stop Transmission of Poliomyelitis, Abuja, Nigeria.; Fadahunsi R; African Field Epidemiology Network, Abuja, Nigeria.; National Stop Transmission of Poliomyelitis, Abuja, Nigeria.; Wisdom M; African Field Epidemiology Network, Abuja, Nigeria.; National Stop Transmission of Poliomyelitis, Abuja, Nigeria.; Akudo OL; African Field Epidemiology Network, Abuja, Nigeria.; National Stop Transmission of Poliomyelitis, Abuja, Nigeria.; Ugbenyo G; African Field Epidemiology Network, Abuja, Nigeria.; National Stop Transmission of Poliomyelitis, Abuja, Nigeria.; Simple E; African Field Epidemiology Network, Abuja, Nigeria.; National Stop Transmission of Poliomyelitis, Abuja, Nigeria.; Waziri N; African Field Epidemiology Network, Abuja, Nigeria.; National Stop Transmission of Poliomyelitis, Abuja, Nigeria.; Vasumu JJ; Adamawa State Primary Health Care Development Agency, Yola, Adamawa State, Nigeria.; Bahuli AU; Adamawa State Primary Health Care Development Agency, Yola, Adamawa State, Nigeria.; Bashir SS; Adamawa State Primary Health Care Development Agency, Yola, Adamawa State, Nigeria.; Isa A; Adamawa State Primary Health Care Development Agency, Yola, Adamawa State, Nigeria.; Ugwu GO; Department of Obstetrics and Gynaecology, College of Medicine, University of Nsukka, Nsukka, Nigeria.; Enugu State Primary Health Care Development Agency, Enugu, Nigeria.; Obi EI; National Emergency Routine Immunization Coordination Centre, Abuja, Nigeria.; Binta H; National Emergency Routine Immunization Coordination Centre, Abuja, Nigeria.; Department of Community Medicine, Faculty of Medical Sciences, College of Medicine, University of Nigeria/ University of Nigeria Teaching Hospital, Enugu, Nigeria.; Bassey BO; National Primary Health Care Development Agency, Abuja, Nigeria.; Shuaib F; National Primary Health Care Development Agency, Abuja, Nigeria.; Bolu O; Global Immunization Division, United States, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.; Centers for Disease Control and Prevention Nigeria, Abuja, Nigeria.; Tohme RA; Global Immunization Division, United States, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Source
Publisher: Public Library of Science Country of Publication: United States NLM ID: 9918283779606676 Publication Model: eCollection Cited Medium: Internet ISSN: 2767-3375 (Electronic) Linking ISSN: 27673375 NLM ISO Abbreviation: PLOS Glob Public Health Subsets: PubMed not MEDLINE
Subject
Language
English
Abstract
Nigeria is estimated to have the largest number of children worldwide, living with chronic hepatitis B virus (HBV) infection, the leading cause of liver cancer. Up to 90% of children infected at birth develop chronic HBV infection. A birth dose of the hepatitis B vaccine (HepB-BD) followed by at least two additional vaccine doses is recommended for prevention. This study assessed barriers and facilitators of HepB-BD administration and uptake, using structured interviews with healthcare providers and pregnant women in Adamawa and Enugu States, Nigeria. The Consolidated Framework for Implementation Sciences Research (CFIR) guided data collection and analysis. We interviewed 87 key informants (40 healthcare providers and 47 pregnant women) and created a codebook for data analysis. Codes were developed by reviewing the literature and reading a subsample of queries line-by-line. The overarching themes identified as barriers among healthcare providers were: the lack of hepatitis B knowledge, limited availability of HepB-BD to vaccination days only, misconceptions about HepB-BD vaccination, challenges in health facility staffing capacity, costs associated with vaccine transportation, and concerns related to vaccine wastage. Facilitators of timely HepB-BD vaccination included: vaccine availability, storage, and hospital births occurring during immunization days. Overarching themes identified as barriers among pregnant women were lack of hepatitis B knowledge, limited understanding of HepB-BD importance, and limited access to vaccines for births occurring outside of a health facility. Facilitators were high vaccine acceptance and willingness for their infants to receive HepB-BD if recommended by providers. Findings indicate the need for enhanced HepB-BD vaccination training for HCWs, educating pregnant women on HBV and the importance of timely HepB-BD, updating policies to enable HepB-BD administration within 24 hours of birth, expanding HepB-BD availability in public and private hospital maternity wards for all facility births, and outreach activities to reach home births.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.)
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.)