학술논문
Pulmonary function and body composition parameters of children with cystic fibrosis from a hight complexity institution between 2015 and 2018.
Document Type
Academic Journal
Author
Salazar-Solarte AM; Pediatrics Department, Hospital Universitario Fundación Valle del Lili, Cali, Colombia; Faculty of Health Sciences, Universidad Icesi, Cali, Colombia; Interdisciplinary Research Group in Epidemiology and Public Health, Universidad Libre, Seccional, Cali, Colombia. Electronic address: auramaria1114@gmail.com.; Torres-Canchala L; Investigation Center, Fundación Valle del Lili, Cali, Colombia.; Carrera-Gil F; Faculty of Health Sciences, Pontificia Universidad Javeriana, Cali, Colombia.; Quimbayo-Wilches DM; Pediatrics Department, Hospital Universitario Fundación Valle del Lili, Cali, Colombia; Faculty of Health Sciences, Universidad Icesi, Cali, Colombia; Pediatrics and Gastroenterology Department. Hospital Universitario Fundación Valle del Lili, Cali, Colombia.
Source
Publisher: Elsevier Country of Publication: Singapore NLM ID: 101484755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-1692 (Electronic) Linking ISSN: 18759572 NLM ISO Abbreviation: Pediatr Neonatol Subsets: MEDLINE
Subject
Language
English
Abstract
Background: An adequate nutritional status in patients with cystic fibrosis correlates with higher survival and better pulmonary function. Body mass index (BMI) is an anthropometric indicator with independent association with pulmonary function, and it can hide alterations of nutritional status in cystic fibrosis.
Objective: To determine the relationship of lung function with BMI and body composition parameters in children with cystic fibrosis in a Hight Complexity institution between 2015 and 2018.
Materials and Methods: It was an observational study with analytical, cross-sectional, and retrospective scope, including 33 patients between 5 and 17 years old. Spearman's test was applied to evaluate correlation of FEV1 (forced expiratory volume in first second) with BMI and five body composition parameters by bioelectrical impedance using InbodyS10 equipment. Statistical significance was considered with p < 0.05.
Results: Positive correlation was obtained between FEV1 and appendicular skeletal muscle mass between lung function and percentage of fat-free mass (p = 0.006) and phase angle (p = 0.001). Percent fat mass had a negative correlation with FEV1 (p = 0.007). BMI and fat free mass index did not correlate with lung function (p = 0.085).
Conclusions: Appendicular skeletal muscle mass correlated better than BMI with lung function in children with cystic fibrosis. It is recommended to perform anthropometric follow-up by BMI complemented with body composition study in children with cystic fibrosis. Analyses with larger populations are required to standardize its use.
Competing Interests: Declaration of competing interest The authors have no conflicts of interest related to this article.
(Copyright © 2024 Taiwan Pediatric Association. Published by Elsevier B.V. All rights reserved.)
Objective: To determine the relationship of lung function with BMI and body composition parameters in children with cystic fibrosis in a Hight Complexity institution between 2015 and 2018.
Materials and Methods: It was an observational study with analytical, cross-sectional, and retrospective scope, including 33 patients between 5 and 17 years old. Spearman's test was applied to evaluate correlation of FEV1 (forced expiratory volume in first second) with BMI and five body composition parameters by bioelectrical impedance using InbodyS10 equipment. Statistical significance was considered with p < 0.05.
Results: Positive correlation was obtained between FEV1 and appendicular skeletal muscle mass between lung function and percentage of fat-free mass (p = 0.006) and phase angle (p = 0.001). Percent fat mass had a negative correlation with FEV1 (p = 0.007). BMI and fat free mass index did not correlate with lung function (p = 0.085).
Conclusions: Appendicular skeletal muscle mass correlated better than BMI with lung function in children with cystic fibrosis. It is recommended to perform anthropometric follow-up by BMI complemented with body composition study in children with cystic fibrosis. Analyses with larger populations are required to standardize its use.
Competing Interests: Declaration of competing interest The authors have no conflicts of interest related to this article.
(Copyright © 2024 Taiwan Pediatric Association. Published by Elsevier B.V. All rights reserved.)