학술논문

Neurological Disorders and Women's Health: Contribution of Molecular Neuroimaging Techniques.
Document Type
Academic Journal
Author
Ekmekcioglu O; Department of Nuclear Medicine, University of Health Sciences, Sisli Hamidiye Etfal Education and Research Hospital, Istanbul, Turkey. Electronic address: ozgulek@gmail.com.; Albert NL; Department of Nuclear Medicine, LMU University Hospital, Ludwig-Maximilians-University, Munich, Germany.; Heinrich K; Department of Medicine III, LMU University Hospital, Ludwig-Maximilians-University, Munich, Germany.; Tolboom N; Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.; Van Weehaeghe D; Department of Radiology and Nuclear Medicine, Ghent University Hospital, Ghent, Belgium.; Traub-Weidinger T; Division of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.; Atay LO; Department of Nuclear Medicine, Gazi University, Ankara, Turkey.; Garibotto V; Division of Nuclear Medicine and Molecular Imaging, Diagnostic Department, University Hospitals of Geneva, Faculty of Medicine, University of Geneva, CIBM Center for Biomedical Imaging, Geneva, Switzerland.; Morbelli S; Nuclear Medicine Unit, AOU Città Della Salute e Della Scienza di Torino, University of Turin, Turin, Italy.
Source
Publisher: W.B. Saunders Country of Publication: United States NLM ID: 1264464 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-4623 (Electronic) Linking ISSN: 00012998 NLM ISO Abbreviation: Semin Nucl Med Subsets: MEDLINE
Subject
Language
English
Abstract
Sex differences in brain physiology and the mechanisms of drug action have been extensively reported. These biological variances, from structure to hormonal and genetic aspects, can profoundly influence healthy functioning and disease mechanisms and might have implications for treatment and drug development. Molecular neuroimaging techniques may help to disclose sex's impact on brain functioning, as well as the neuropathological changes underpinning several diseases. This narrative review summarizes recent lines of evidence based on PET and SPECT imaging, highlighting sex differences in normal conditions and various neurological disorders.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Valentina Garibotto reports a relationship with Swiss National Science Foundation, by the Velux foundation, by the Schmidheiny foundation, the Boninchi foundation and by the Aetas foundation that includes: funding grants. Nathalie L Albert reports a relationship with Novartis Advanced Accelerator Applications, Telix Pharmaceuticals, Servier, Novocure that includes: consulting or advisory and funding grants. Silvia Morbelli reports a relationship with Italian Ministry of University and Research that includes: funding grants. Kathrin Heinrich reports a relationship with Roche, Taiho, BMS, Merck, Servier, MSD (Institutional), Merck, Janssen, Amgen, Merck, Servier that includes: funding grants and travel reimbursement. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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