학술논문
Knowledge and practice of community pharmacists regarding the safety of drugs during pregnancy: a cross-sectional study from a developing country.
Document Type
Academic Journal
Author
Koni AA; Department of Clinical and Community Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.; Division of Clinical Pharmacy, Department of Hematology and Oncology, An-Najah National University Hospital, Nablus, 44839, Palestine.; Qashoa H; Department of Clinical and Community Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.; Musa AA; Department of Clinical and Community Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.; Masri M; Department of Clinical and Community Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.; Hazem W; Department of Clinical and Community Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.; Taha S; Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.; Daifallah A; Department of Clinical and Community Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.; Al-Jabi SW; Department of Clinical and Community Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.; Abushanab AS; Department of Clinical and Community Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.; Zyoud SH; Department of Clinical and Community Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine. saedzyoud@yahoo.com.; Poison Control and Drug Information Center (PCDIC), Faculty of Medicine and Health Sciences, An- Najah National University, Nablus, 44839, Palestine. saedzyoud@yahoo.com.; Clinical Research Center, An-Najah National University Hospital, Nablus, 44839, Palestine. saedzyoud@yahoo.com.
Source
Publisher: BioMed Central Country of Publication: England NLM ID: 100967799 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2393 (Electronic) Linking ISSN: 14712393 NLM ISO Abbreviation: BMC Pregnancy Childbirth Subsets: MEDLINE
Subject
Language
English
Abstract
Background: Drug use during pregnancy can cause unfavorable fetal and maternal outcomes. Information sharing is essential for pharmacists' role within intricate, modern healthcare systems. Community pharmacists (CPs) have demonstrated unsatisfactory knowledge across various pharmacological domains in most developing countries. This study aimed to explore the knowledge and practices of CPs regarding medications and herb safety during pregnancy.
Methods: A cross-sectional study was conducted in a developing country using a self-administered questionnaire. A sample of CPs working in the northern governorates of the West Bank was selected by convenience sampling. The questionnaire included questions on sociodemographic characteristics, practices and knowledge. Descriptive and inferential statistics were calculated using the Statistical Package for the Social Sciences (SPSS) to analyze the data.
Results: A total of 207 questionnaires were completed. Most respondents had only a bachelor's degree (89.9%) but did not participate in continuous professional development (CPD) (71.0%). Almost one-third of the CP workload involved dispensing drugs to pregnant women. The majority of the participants reported that they inquire about pregnancy status (59.9%), refer to scientific sources (82.6%), and contact a prescribing physician (51.2%) in cases of uncertainty. A higher knowledge score was associated with receiving a master's degree and CPD programs. Most CPs identified folic acid, paracetamol and amoxicillin as safe, while tetracycline, isotretinoin, enalapril, pseudoephedrine and ibuprofen were among the drugs mostly reported as unsafe. Castor oil, Senna, St. John's wort and ginseng were the most frequently reported herbs as unsafe.
Conclusions: Despite the gaps in knowledge about herb pharmacology, CPs demonstrated acceptable knowledge and practice regarding drug safety during pregnancy. CPD is recommended for addressing gaps in knowledge and practice. Future research evaluating knowledge and practice may benefit from developing a specific, accurate, validated instrument.
(© 2024. The Author(s).)
Methods: A cross-sectional study was conducted in a developing country using a self-administered questionnaire. A sample of CPs working in the northern governorates of the West Bank was selected by convenience sampling. The questionnaire included questions on sociodemographic characteristics, practices and knowledge. Descriptive and inferential statistics were calculated using the Statistical Package for the Social Sciences (SPSS) to analyze the data.
Results: A total of 207 questionnaires were completed. Most respondents had only a bachelor's degree (89.9%) but did not participate in continuous professional development (CPD) (71.0%). Almost one-third of the CP workload involved dispensing drugs to pregnant women. The majority of the participants reported that they inquire about pregnancy status (59.9%), refer to scientific sources (82.6%), and contact a prescribing physician (51.2%) in cases of uncertainty. A higher knowledge score was associated with receiving a master's degree and CPD programs. Most CPs identified folic acid, paracetamol and amoxicillin as safe, while tetracycline, isotretinoin, enalapril, pseudoephedrine and ibuprofen were among the drugs mostly reported as unsafe. Castor oil, Senna, St. John's wort and ginseng were the most frequently reported herbs as unsafe.
Conclusions: Despite the gaps in knowledge about herb pharmacology, CPs demonstrated acceptable knowledge and practice regarding drug safety during pregnancy. CPD is recommended for addressing gaps in knowledge and practice. Future research evaluating knowledge and practice may benefit from developing a specific, accurate, validated instrument.
(© 2024. The Author(s).)