학술논문
Cuffless Blood Pressure Measurement Using a Smartphone-Case Based ECG Monitor with Photoplethysmography in Hypertensive Patients.
Document Type
Academic Journal
Author
Sagirova Z; Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky, Institute for Clinical Medicine, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.; Kuznetsova N; Research Center 'Digital Biodesign and Personalized Healthcare', I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Gogiberidze N; Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky, Institute for Clinical Medicine, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.; Gognieva D; Research Center 'Digital Biodesign and Personalized Healthcare', I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Suvorov A; Centre for Analysis of Complex Systems, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Chomakhidze P; Research Center 'Digital Biodesign and Personalized Healthcare', I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Omboni S; Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky, Institute for Clinical Medicine, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.; Italian Institute of Telemedicine, 21048 Solbiate Arno, Italy.; Saner H; Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky, Institute for Clinical Medicine, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.; ARTORG Center for Biomedical Engineering Research, University of Bern, 3008 Bern, Switzerland.; Institute for Social and Preventive Medicine, University of Bern, 3012 Bern, Switzerland.; Kopylov P; Research Center 'Digital Biodesign and Personalized Healthcare', I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Source
Publisher: MDPI Country of Publication: Switzerland NLM ID: 101204366 Publication Model: Electronic Cited Medium: Internet ISSN: 1424-8220 (Electronic) Linking ISSN: 14248220 NLM ISO Abbreviation: Sensors (Basel) Subsets: MEDLINE
Subject
Language
English
Abstract
The availability of simple, accurate, and affordable cuffless blood pressure (BP) devices has the potential to greatly increase the compliance with measurement recommendations and the utilization of BP measurements for BP telemonitoring. The aim of this study is to evaluate the correlation between findings from routine BP measurements using a conventional sphygmomanometer with the results from a portable ECG monitor combined with photoplethysmography (PPG) for pulse wave registration in patients with arterial hypertension.
Methods: The study included 500 patients aged 32-88 years (mean 64 ± 7.9 years). Mean values from three routine BP measurements by a sphygmomanometer with cuff were selected for comparison; within one minute after the last measurement, an electrocardiogram (ECG) was recorded for 3 min in the standard lead I using a smartphone-case based single-channel ECG monitor (CardioQVARK® -limited responsibility company "L-CARD", Moscow, Russia) simultaneously with a PPG pulse wave recording. Using a combination of the heart signal with the PPG, levels of systolic and diastolic BP were determined based on machine learning using a previously developed and validated algorithm and were compared with sphygmomanometer results.
Results: According to the Bland-Altman analysis, SD for systolic BP was 3.63, and bias was 0.32 for systolic BP. SD was 2.95 and bias was 0.61 for diastolic BP. The correlation between the results from the sphygmomanometer and the cuffless method was 0.89 ( p = 0.001) for systolic and 0.87 ( p = 0.002) for diastolic BP.
Conclusion: Blood pressure measurements on a smartphone-case without a cuff are encouraging. However, further research is needed to improve the accuracy and reliability of clinical use in the majority of patients.
Methods: The study included 500 patients aged 32-88 years (mean 64 ± 7.9 years). Mean values from three routine BP measurements by a sphygmomanometer with cuff were selected for comparison; within one minute after the last measurement, an electrocardiogram (ECG) was recorded for 3 min in the standard lead I using a smartphone-case based single-channel ECG monitor (CardioQVARK
Results: According to the Bland-Altman analysis, SD for systolic BP was 3.63, and bias was 0.32 for systolic BP. SD was 2.95 and bias was 0.61 for diastolic BP. The correlation between the results from the sphygmomanometer and the cuffless method was 0.89 ( p = 0.001) for systolic and 0.87 ( p = 0.002) for diastolic BP.
Conclusion: Blood pressure measurements on a smartphone-case without a cuff are encouraging. However, further research is needed to improve the accuracy and reliability of clinical use in the majority of patients.