학술논문
Emergence of New SARS-CoV2 Omicron Variants after the Change of Surveillance and Control Strategy.
Document Type
Academic Journal
Author
Alba JMG; Unit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; Pérez-Martínez Z; Unit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; Boga JA; Unit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; Rojo-Alba S; Unit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; de Oña JG; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; Genetic Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; Alvarez-Argüelles ME; Unit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; Rodríguez GM; Unit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; Gonzalez IC; Unit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; González IH; Epidemiological Surveillance Department, 33011 Oviedo, Spain.; Coto E; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; Genetic Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; García SM; Unit of Virology, Microbiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.; Instituto de Investigación Sanitario del Principado de Asturias (ISPA), 33011 Oviedo, Spain.
Source
Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101625893 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2607 (Print) Linking ISSN: 20762607 NLM ISO Abbreviation: Microorganisms Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2076-2607
Abstract
In January 2022, there was a global and rapid surge of the Omicron variant of SARS-CoV-2 related to more transmission. This coincided with an increase in the incidence in Asturias, a region where rapid diagnosis and containment measures had limited the circulation of variants.
Methods: From January to June 2022, 34,591 variants were determined by the SNP method. From them, 445 were characterized by the WGS method and classified following pangolin program and phylogenic analysis.
Results: The Omicron variant went from being detected in 2438 (78%) samples in the first week of January 2021 to 4074 (98%) in the third week, according to the SNP method. Using the WGS method, 159 BA.1 (35.7%), 256 BA.2 (57.6%), 1 BA.4 (0.2%) and 10 BA.5 (2.2%) Omicron variants were found. Phylogenetic analysis detected that three new sub-clades, BA.2,3.5, BA.2.56 and BF1, were circulating.
Conclusions: The increase in the incidence of SARS-CoV2 caused the circulation of new emerging variants. Viral evolution calls for continuous genomic surveillance.
Methods: From January to June 2022, 34,591 variants were determined by the SNP method. From them, 445 were characterized by the WGS method and classified following pangolin program and phylogenic analysis.
Results: The Omicron variant went from being detected in 2438 (78%) samples in the first week of January 2021 to 4074 (98%) in the third week, according to the SNP method. Using the WGS method, 159 BA.1 (35.7%), 256 BA.2 (57.6%), 1 BA.4 (0.2%) and 10 BA.5 (2.2%) Omicron variants were found. Phylogenetic analysis detected that three new sub-clades, BA.2,3.5, BA.2.56 and BF1, were circulating.
Conclusions: The increase in the incidence of SARS-CoV2 caused the circulation of new emerging variants. Viral evolution calls for continuous genomic surveillance.