학술논문
Neurological Manifestations of Chronic Methadone Maintenance Therapy: A Case Report and Literature Review.
Document Type
Report
Author
Gasimova U; Neurology, Saint Louis University School of Medicine, St. Louis, USA.; Afzal KM; Neurology, Saint Louis University School of Medicine, St. Louis, USA.; Acharya AB; Neurology, Saint Louis University School of Medicine, St. Louis, USA.
Source
Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2168-8184
Abstract
Methadone is a long-acting opioid medication that is used as maintenance therapy for heroin addiction. We present a case of a patient on methadone maintenance therapy for chronic back pain who developed neurological complications. The patient presented with mental status changes and choreiform movements. Workup revealed lesions involving the subcortical white matter and basal ganglia. Choreiform movements improved after the initiation of treatment with topiramate, clonazepam, and risperidone. This combination was chosen as several prior case reports published significant benefit and improvement in choreiform movements with the mentioned regimen.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Gasimova et al.)
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Gasimova et al.)