학술논문
The possible role of hyperhomocysteinemia on IVF outcome.
Document Type
Academic Journal
Author
Pacchiarotti A; Obstetric and Gynecology, Policlinico Umberto, La Sapienza University of Rome, Viale Regina Elena, Rome, Italy. arypac@aliceposta.it; Mohamed MA; Micara G; Linari A; Tranquilli D; Espinola SB; Aragona C
Source
Publisher: Springer Country of Publication: Netherlands NLM ID: 9206495 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1058-0468 (Print) Linking ISSN: 10580468 NLM ISO Abbreviation: J Assist Reprod Genet Subsets: MEDLINE
Subject
Language
English
ISSN
1058-0468
Abstract
Purpose: To evaluate the effect of the hyperhomocysteinemia on pregnancy rate, implantation rate and abortion rate after IVF.
Method: Data from a total of 48 infertile couples with hyperhomocysteinemia were prospectively collected for this study. All patients underwent a standard down regulation protocol for ovarian stimulation. Oocytes recovery was performed at 36 h after hCG administration. Embryo transfer took place at 48 h after insemination. The patients were matched in two groups that received or did not receive therapy (group A and B respectively) to normalize homocysteine plasma level.
Results: Pregnancy rate, implantation rate and abortion rate varied significantly (p
Method: Data from a total of 48 infertile couples with hyperhomocysteinemia were prospectively collected for this study. All patients underwent a standard down regulation protocol for ovarian stimulation. Oocytes recovery was performed at 36 h after hCG administration. Embryo transfer took place at 48 h after insemination. The patients were matched in two groups that received or did not receive therapy (group A and B respectively) to normalize homocysteine plasma level.
Results: Pregnancy rate, implantation rate and abortion rate varied significantly (p