학술논문
[Association between paracetamol exposure and asthma: update and practice guidelines].
Document Type
Academic Journal
Author
Moral L; Unidad de Alergología y Neumología Pediátrica, Hospital General Universitario de Alicante, Alicante, España. lmoralg@gmail.com; Torres-Borrego J; Korta Murua J; Valverde-Molina J; Pellegrini Belinchón J; Praena-Crespo M; Ortega Casanueva C; Callén-Blecua MT; Fernández-Llamazares CM; Calvo Rey C
Source
Publisher: Elsevier España Country of Publication: Spain NLM ID: 101162596 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1695-9531 (Electronic) Linking ISSN: 16954033 NLM ISO Abbreviation: An Pediatr (Barc) Subsets: MEDLINE
Subject
Language
Spanish; Castilian
Abstract
Asthma prevalence has increased over the last few decades, especially in developed countries, and possibly due to different reasons. An association between paracetamol use or exposure at different periods of life, including gestation and childhood, and asthma prevalence has been observed in the last few years. Causality can not be established from observational reports, due to the arguable presence of many confounding factors and biases. Randomised trials are needed to elucidate the nature of this association. The Spanish Paediatric societies subscribing to this paper consider that current evidence is insufficient to discourage the use of paracetamol during gestation or in children with or at risk of asthma.
(Copyright © 2012 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.)
(Copyright © 2012 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.)