학술논문
Quality of Life in Older Patients after a Heart Failure Hospitalization: Results from the SENECOR Study.
Document Type
Academic Journal
Author
Luiso D; Heart Failure Unit, Cardiology Department, Hospital del Mar, 08003 Barcelona, Spain.; Department of Medicine, Universitat Autónoma de Barcelona, 08193 Barcelona, Spain.; Herrero-Torrus M; Geriatrics Department, Hospital del Mar, 08003 Barcelona, Spain.; Badosa N; Heart Failure Unit, Cardiology Department, Hospital del Mar, 08003 Barcelona, Spain.; Biomedical Research Group on Heart Disease, Hospital del Mar Medical Research Group (IMIM), 08003 Barcelona, Spain.; Roqueta C; Department of Medicine, Universitat Autónoma de Barcelona, 08193 Barcelona, Spain.; Geriatrics Department, Hospital del Mar, 08003 Barcelona, Spain.; Ruiz-Bustillo S; Heart Failure Unit, Cardiology Department, Hospital del Mar, 08003 Barcelona, Spain.; Biomedical Research Group on Heart Disease, Hospital del Mar Medical Research Group (IMIM), 08003 Barcelona, Spain.; Department of Medicine, Universidad Pompeu Fabra, 08002 Barcelona, Spain.; Belarte-Tornero LC; Heart Failure Unit, Cardiology Department, Hospital del Mar, 08003 Barcelona, Spain.; Biomedical Research Group on Heart Disease, Hospital del Mar Medical Research Group (IMIM), 08003 Barcelona, Spain.; Valdivielso-Moré S; Heart Failure Unit, Cardiology Department, Hospital del Mar, 08003 Barcelona, Spain.; Biomedical Research Group on Heart Disease, Hospital del Mar Medical Research Group (IMIM), 08003 Barcelona, Spain.; Morales RO; Heart Failure Unit, Cardiology Department, Hospital del Mar, 08003 Barcelona, Spain.; Vázquez O; Geriatrics Department, Hospital del Mar, 08003 Barcelona, Spain.; Farré N; Heart Failure Unit, Cardiology Department, Hospital del Mar, 08003 Barcelona, Spain.; Department of Medicine, Universitat Autónoma de Barcelona, 08193 Barcelona, Spain.; Biomedical Research Group on Heart Disease, Hospital del Mar Medical Research Group (IMIM), 08003 Barcelona, Spain.
Source
Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2077-0383
Abstract
Background: Information about health-related quality of life (HRQoL) in heart failure (HF) in older adults is scarce. Methods: We aimed to describe the HRQoL of the SENECOR study cohort, a single-center, randomized trial comparing the effects of multidisciplinary intervention by a geriatrician and a cardiologist (intervention group) to that of a cardiologist alone (control group) in older patients with a recent HF hospitalization. Results: HRQoL was assessed by the short version of the disease-specific Kansas Cardiomyopathy Questionnaire (KCCQ-12) in 141 patients at baseline and was impaired (KCCQ-12 < 75) in almost half of the cohort. Women comprised 50% of the population, the mean age was 82.2 years, and two-thirds of patients had preserved ejection fraction. Comorbidities were highly prevalent. Patients with impaired HRQoL had a worse NYHA functional class, a lower NT-proBNP, a lower Barthel index, and a higher Clinical Frailty Scale. One-year all-cause mortality was 22.7%, significantly lower in the group with good-to-excellent HRQoL (14.5% vs. 30.6%; hazard ratio 0.28; 95% confidence interval 0.10−0.78; p = 0.014). In the group with better HRQoL, all-cause hospitalization was lower, and there was a trend towards lower HF hospitalization. Conclusions: The KCCQ-12 questionnaire can provide inexpensive prognostic information even in older patients with HF. (Funded by grant Primitivo de la Vega, Fundación MAPFRE. ClinicalTrials number, NCT03555318).