학술논문
A novel id-iri score: development and internal validation of the multivariable community acquired sepsis clinical risk prediction model.
Document Type
Academic Journal
Author
Diktas H; Department of Infectious Diseases and Clinical Microbiology, Şişli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey.; Uysal S; Department of Infectious Diseases and Clinical Microbiology, Kanuni Research and Training Hospital, Trabzon, Turkey.; Erdem H; Department of Infectious Diseases and Clinical Microbiology, Gulhane Research and Training Hospital, Ankara, Turkey. hakanerdem1969@yahoo.com.; Cag Y; Department of Infectious Diseases and Clinical Microbiology, Medeniyet University, Goztepe Training and Research Hospital, İstanbul, Turkey.; Miftode E; Department of Infectious Diseases, Sf. Parascheva Infectious Diseases Clinical Hospital, Iasi, Romania.; Durmus G; Department of Infectious Diseases and Clinical Microbiology, Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey.; Ulu-Kilic A; Department of Infectious Disease and Clinical Microbiology, Erciyes University Medical School, Kayseri, Turkey.; Alabay S; Department of Infectious Disease and Clinical Microbiology, Erciyes University Medical School, Kayseri, Turkey.; Szabo BG; Joined St. Stephan and St. Ladislaus Hospital-Clinic, Budapest, Hungary.; Lakatos B; Joined St. Stephan and St. Ladislaus Hospital-Clinic, Budapest, Hungary.; Fernandez R; Department of Pulmonary and Critical Care, San Juan City Hospital, San Juan, Puerto Rico.; Korkmaz P; Department of Clinical Microbiology and Infectious Diseases, Faculty of Medicine, Dumlupınar University, Kutahya, Turkey.; Caliz MC; Department of Pulmonary and Critical Care, San Juan City Hospital, San Juan, Puerto Rico.; Argemi X; Service des Maladies Infectieuses et Tropicales, Hôpitaux Universitaires, Strasbourg, France.; Kulzhanova S; Department of Infectious Diseases and Epidemiology, Medical University Astana, Astana, Kazakhstan.; Kormaz F; Department of Infectious Diseases and Clinical Microbiology, Konya Training and Research Hospital, Konya, Turkey.; Yilmaz-Karadag F; Department of Infectious Diseases and Clinical Microbiology, Medeniyet University, Goztepe Training and Research Hospital, İstanbul, Turkey.; Ergen P; Department of Infectious Diseases and Clinical Microbiology, Medeniyet University, Goztepe Training and Research Hospital, İstanbul, Turkey.; Atilla A; Department of Infectious Diseases and Clinical Microbiology, Samsun Research and Training Hospital, Samsun, Turkey.; Puca E; University Hospital Center, Tirana, Albania.; Dogan M; Department of Infectious Diseases and Clinical Microbiology, Corlu State Hospital, Tekirdag, Turkey.; Mangani F; Diagnostics and Public Health, Policlinico GB Rossi-Verona, Verona, Italy.; Sahin S; Department of Infectious Diseases and Clinical Microbiology, Kartal Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey.; Grgić S; Clinic for Infectious Diseases, University Clinical Hospital Mostar, School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina.; Grozdanovski K; Department of Intensive Care, University Clinic for Infectious Diseases, Skopje, Macedonia.; Yilmaz GR; Department of Infectious Diseases and Clinical Microbiology, Ankara Ataturk Training and Research Hospital, Bilkent, Ankara, Turkey.; Del-Vecchio RF; Department of Clinical and Molecular Biomedicine, Division of Infectious Diseases, University of Catania, Garibaldi Nesima Hospital, Catania, Italy.; Demirel A; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Bilim University, Istanbul, Turkey.; Sirmatel F; Department of Infectious Diseases and Clinical Microbiology, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.; Şener A; Department of Infectious Diseases and Clinical Microbiology, Onsekiz Mart University School of Medicine, Canakkale, Turkey.; Sacar S; Department of Infectious Diseases and Clinical Microbiology, Onsekiz Mart University School of Medicine, Canakkale, Turkey.; Aydin E; Department of Infectious Diseases and Clinical Microbiology, Kafkas University School of Medicine, Kars, Turkey.; Batirel A; Department of Infectious Diseases and Clinical Microbiology, Kartal Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey.; Dragovac G; Centre of Disease Prevention and Control, Institute of Public Health of Vojvodina, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.; El-Sokkary R; Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.; Alexandru C; Department of Infectious Diseases, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.; Arslan-Ozel S; Department of Infectious Diseases and Clinical Microbiology, Derince Training Hospital, Kocaeli, Turkey.; Bolukcu S; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.; Ozkaya HD; Department of Infectious Diseases and Clinical Microbiology, Cigli Regional Education Hospital, Izmir, Turkey.; Nayman-Alpat S; Department of Infectious Disease and Clinical Microbiology, Faculty of Medicine, Osmangazi University, Eskisehir, Turkey.; Inan A; Department of Infectious Diseases and Clinical Microbiology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.; Al-Majid F; Department of Medicine, Infectious Diseases Division, King Saud University Hospital, Riyadh, Saudi Arabia.; Kaya-Ugur B; Department of Anesthesiology and Reanimation, Gaziantep University School of Medicine, Gaziantep, Turkey.; Rello J; Critical Care Department, Hospital Vall d'Hebron, Ciberes, Universitat Autonma de Barcelona, Barcelona, Spain.
Source
Publisher: Springer Country of Publication: Germany NLM ID: 8804297 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-4373 (Electronic) Linking ISSN: 09349723 NLM ISO Abbreviation: Eur J Clin Microbiol Infect Dis Subsets: MEDLINE
Subject
Language
English
Abstract
We aimed to develop a scoring system for predicting in-hospital mortality of community-acquired (CA) sepsis patients. This was a prospective, observational multicenter study performed to analyze CA sepsis among adult patients through ID-IRI (Infectious Diseases International Research Initiative) at 32 centers in 10 countries between December 1, 2015, and May 15, 2016. After baseline evaluation, we used univariate analysis at the second and logistic regression analysis at the third phase. In this prospective observational study, data of 373 cases with CA sepsis or septic shock were submitted from 32 referral centers in 10 countries. The median age was 68 (51-77) years, and 174 (46,6%) of the patients were females. The median hospitalization time of the patients was 15 (10-21) days. Overall mortality rate due to CA sepsis was 17.7% (n = 66). The possible predictors which have strong correlation and the variables that cause collinearity are acute oliguria, altered consciousness, persistent hypotension, fever, serum creatinine, age, and serum total protein. CAS (%) is a new scoring system and works in accordance with the parameters in third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). The system has yielded successful results in terms of predicting mortality in CA sepsis patients.