학술논문
Positive and negative survivor-specific psychosocial consequences of childhood cancer: the DCCSS-LATER 2 psycho-oncology study.
Document Type
Academic Journal
Author
Maas A; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands. a.maas-9@prinsesmaximacentrum.nl.; Maurice-Stam H; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; van der Aa-van Delden AM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; van Dalen EC; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; van Dulmen-den Broeder E; Amsterdam UMC/Location VUmc, Amsterdam, The Netherlands.; Tissing WJE; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Beatrix Children's Hospital, University of Groningen/University Medical Center Groningen, Groningen, The Netherlands.; Loonen JJ; Radboud University Medical Center, Nijmegen, The Netherlands.; van der Pal HJH; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; de Vries ACH; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, The Netherlands.; van den Heuvel-Eibrink MM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, The Netherlands.; Janssens GO; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.; Ronckers C; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Division of Childhood Cancer Epidemiology, Institute of Medical Biostatistics Informatics and Epidemiology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; Neggers S; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Medicine, Section Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands.; Bresters D; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Willem Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.; Louwerens M; Leiden University Medical Center, Leiden, The Netherlands.; Versluys BAB; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, The Netherlands.; van der Heiden-van der Loo M; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Kremer LCM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pediatrics, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; van Gorp M; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Grootenhuis MA; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Source
Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 101307557 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-2267 (Electronic) Linking ISSN: 19322259 NLM ISO Abbreviation: J Cancer Surviv Subsets: MEDLINE
Subject
Language
English
Abstract
Purpose: Numerous studies investigated generic psychosocial outcomes in survivors of childhood cancer (CCS). The present study aimed to describe survivor-specific psychosocial consequences in CCS, and to identify socio-demographic and medical associated factors.
Methods: CCS from the Dutch Childhood Cancer Survivor Study (DCCSS)-LATER cohort (diagnosed 1963-2001) part 2 (age ≥ 18 years, diagnosed < 18 years, ≥ 5 years since diagnosis) completed the Benefit & Burden Scale (BBSC) and the Impact of Cancer-Childhood Cancer (IOC-CS). Items were scored on a 5-point Likert scale (range 1-5). We examined outcomes with descriptive statistics, and socio-demographic and medical associated factors with regression analyses, corrected for multiple testing (p < 0.004).
Results: CCS, N = 1713, age mean (M) 36 years, 49% female, ≥ 15 years since diagnosis, participated. On average, CCS reported 'somewhat' Benefit (M = 2.9), and 'not at all' to 'a little' Burden (M = 1.5) of childhood cancer. Average scores on IOC-CS' positive impact scales ranged from 2.5 (Personal Growth) to 4.1 (Socializing), and on the negative impact scales from 1.4 (Financial Problems) to 2.4 (Thinking/Memory). Apart from cognitive problems, CCS reported challenges as worries about relationship status, fertility, and how cancer had affected siblings. Female sex was associated with more Personal Growth, and more negative impact. CCS more highly educated, partnered, and employed had higher positive and lower negative impact. CCS older at diagnosis reported more positive impact. CNS tumor survivors and those who had head/cranium radiotherapy had higher negative impact. CNS tumor survivors reported less positive impact.
Conclusion and Implications: The majority of CCS reported positive impact of cancer while most CCS reported little negative impact. While this may indicate resiliency in most CCS, health care providers should be aware that they can also experience survivor-specific challenges that warrant monitoring/screening, information provision and psychosocial support.
(© 2023. The Author(s).)
Methods: CCS from the Dutch Childhood Cancer Survivor Study (DCCSS)-LATER cohort (diagnosed 1963-2001) part 2 (age ≥ 18 years, diagnosed < 18 years, ≥ 5 years since diagnosis) completed the Benefit & Burden Scale (BBSC) and the Impact of Cancer-Childhood Cancer (IOC-CS). Items were scored on a 5-point Likert scale (range 1-5). We examined outcomes with descriptive statistics, and socio-demographic and medical associated factors with regression analyses, corrected for multiple testing (p < 0.004).
Results: CCS, N = 1713, age mean (M) 36 years, 49% female, ≥ 15 years since diagnosis, participated. On average, CCS reported 'somewhat' Benefit (M = 2.9), and 'not at all' to 'a little' Burden (M = 1.5) of childhood cancer. Average scores on IOC-CS' positive impact scales ranged from 2.5 (Personal Growth) to 4.1 (Socializing), and on the negative impact scales from 1.4 (Financial Problems) to 2.4 (Thinking/Memory). Apart from cognitive problems, CCS reported challenges as worries about relationship status, fertility, and how cancer had affected siblings. Female sex was associated with more Personal Growth, and more negative impact. CCS more highly educated, partnered, and employed had higher positive and lower negative impact. CCS older at diagnosis reported more positive impact. CNS tumor survivors and those who had head/cranium radiotherapy had higher negative impact. CNS tumor survivors reported less positive impact.
Conclusion and Implications: The majority of CCS reported positive impact of cancer while most CCS reported little negative impact. While this may indicate resiliency in most CCS, health care providers should be aware that they can also experience survivor-specific challenges that warrant monitoring/screening, information provision and psychosocial support.
(© 2023. The Author(s).)