학술논문
The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries.
Document Type
Academic Journal
Author
Şaylık F; Department of Cardiology, Van Education and Research Hospital, Van, Turkey.; Çınar T; Department of Cardiology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.; Sarıkaya R; Department of Cardiology, Van Education and Research Hospital, Van, Turkey.; Akbulut T; Department of Cardiology, Van Education and Research Hospital, Van, Turkey.; Selçuk M; Department of Cardiology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.; Özbek E; Department of Cardiology, Van Education and Research Hospital, Van, Turkey.; Tanboğa Hİ; Department of Cardiology and Biostatistics, Istanbul Nisantasi University, Istanbul, Turkey.
Source
Publisher: Cardiovascular Research Center of Tabriz University of Medical Sciences Country of Publication: Iran NLM ID: 101528712 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2008-5117 (Print) Linking ISSN: 20085117 NLM ISO Abbreviation: J Cardiovasc Thorac Res Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2008-5117
Abstract
Introduction: Coronary collateral circulation (CCC) develops in chronic total occluded (CTO) vessels and protects the myocardium against ischemia in addition to the improvement of cardiac functions. Poor CCC is related to adverse cardiac events as well as poor prognosis. Serum uric acid/albumin ratio (UAR) has emerged as a novel marker associated with poor cardiovascular outcomes. We aimed to investigate whether there was an association between UAR and poor CCC in CTO patients. Methods: This study was comprised of 212 patients with CTO (92 with poor CCC and 120 with good CCC). All patients were graded based on Rentrop scores to poor CCC (Rentrop scores 0 and 1) and good CCC (Rentrop scores 2 and 3). Results: Poor CCC patients had higher frequencies of diabetes mellitus, triglyceride levels, Syntax and Gensini scores, uric acid, and UAR and lower lymphocyte, high-density lipoprotein cholesterol, and ejection fraction when compared to good CCC patients. UAR was an independent predictor of poor CCC in CTO patients. Furthermore, UAR had a better discriminative ability for patients with poor CCC from good CCC compared to serum uric acid and albumin. Conclusion: Based on the results of the study, the UAR could be used to detect poor CCC in CTO patients.
Competing Interests: The authors declared no conflict of interest.
(© 2023 The Author(s).)
Competing Interests: The authors declared no conflict of interest.
(© 2023 The Author(s).)