학술논문
Features of Obstructive Sleep Apnea in Children with and without Comorbidities.
Document Type
Academic Journal
Author
Chiner E; Pulmonology Department, Multidisciplinary Sleep Clinic, San Juan de Alicante University Hospital, 03550 Alicante, Spain.; Sancho-Chust JN; Pulmonology Department, Multidisciplinary Sleep Clinic, San Juan de Alicante University Hospital, 03550 Alicante, Spain.; Pastor E; Pulmonology Department, Multidisciplinary Sleep Clinic, San Juan de Alicante University Hospital, 03550 Alicante, Spain.; Esteban V; Pulmonology Department, Multidisciplinary Sleep Clinic, San Juan de Alicante University Hospital, 03550 Alicante, Spain.; Boira I; Pulmonology Department, Multidisciplinary Sleep Clinic, San Juan de Alicante University Hospital, 03550 Alicante, Spain.; Castelló C; Pulmonology Department, Multidisciplinary Sleep Clinic, San Juan de Alicante University Hospital, 03550 Alicante, Spain.; Celis C; Pulmonology Department, Multidisciplinary Sleep Clinic, San Juan de Alicante University Hospital, 03550 Alicante, Spain.; Vañes S; Pulmonology Department, Multidisciplinary Sleep Clinic, San Juan de Alicante University Hospital, 03550 Alicante, Spain.; Torba A; Pulmonology Department, Multidisciplinary Sleep Clinic, San Juan de Alicante University Hospital, 03550 Alicante, Spain.
Source
Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2077-0383
Abstract
Background: To compare the clinical and polysomnographic features of obstructive sleep apnea (OSA) in children with adenotonsillar hypertrophy (Group A) and comorbidities (Group B).
Methods: A five-year prospective study using nocturnal polysomnography before and after treatment.
Results: We included 168 patients: 121 in Group A and 47 in Group B, with differences in age (6.5 ± 3 vs. 8.6 ± 4 years; p < 0.001), body mass index (BMI) (18 ± 4 vs. 20 ± 7 kg/m2; p < 0.05), neck circumference (28 ± 4 vs. 30 ± 5 cm; p < 0.05), and obesity (17% vs. 30%; p < 0.05). Group B patients were more likely to have facial anomalies ( p < 0.001), macroglossia ( p < 0.01), dolichocephaly ( p < 0.01), micrognathia ( p < 0.001), and prognathism ( p < 0.05). Adenotonsillectomy was performed in 103 Group A patients (85%) and 28 Group B patients (60%) ( p < 0.001). In B, 13 children (28%) received treatment with continuous positive airway pressure (CPAP) and 2 (4%) with bilevel positive airway pressure (BiPAP), compared with 7 in Group A (6%) ( p < 0.001). Maxillofacial surgery was more common in Group B ( p < 0.01). Clinical and polysomnography parameters improved significantly in both groups after therapeutic intervention, though Group A showed better results.
Conclusions: Obesity and facial anomalies are more frequent in childhood OSA patients with comorbidities, who often require combination therapy, such as ventilation and surgery.
Methods: A five-year prospective study using nocturnal polysomnography before and after treatment.
Results: We included 168 patients: 121 in Group A and 47 in Group B, with differences in age (6.5 ± 3 vs. 8.6 ± 4 years; p < 0.001), body mass index (BMI) (18 ± 4 vs. 20 ± 7 kg/m2; p < 0.05), neck circumference (28 ± 4 vs. 30 ± 5 cm; p < 0.05), and obesity (17% vs. 30%; p < 0.05). Group B patients were more likely to have facial anomalies ( p < 0.001), macroglossia ( p < 0.01), dolichocephaly ( p < 0.01), micrognathia ( p < 0.001), and prognathism ( p < 0.05). Adenotonsillectomy was performed in 103 Group A patients (85%) and 28 Group B patients (60%) ( p < 0.001). In B, 13 children (28%) received treatment with continuous positive airway pressure (CPAP) and 2 (4%) with bilevel positive airway pressure (BiPAP), compared with 7 in Group A (6%) ( p < 0.001). Maxillofacial surgery was more common in Group B ( p < 0.01). Clinical and polysomnography parameters improved significantly in both groups after therapeutic intervention, though Group A showed better results.
Conclusions: Obesity and facial anomalies are more frequent in childhood OSA patients with comorbidities, who often require combination therapy, such as ventilation and surgery.