학술논문
Feasibility and safety of stereoelectroencephalography in young children.
Document Type
Academic Journal
Author
Muh CR; Department of Neurosurgery and Department of Pediatrics, Westchester Medical Center, 100 Woods Road, Taylor Pavilion E135, Valhalla, NY, 10595, USA. Carrie.Muh@WMCHealth.org.; Department of Neurosurgery, New York Medical College, Valhalla, NY, 10595, USA. Carrie.Muh@WMCHealth.org.; Dorilio JR; New York Medical College, Valhalla, NY, USA.; Beaudreault CP; New York Medical College, Valhalla, NY, USA.; McGoldrick PE; Department of Pediatric Neurology, Boston Children's Health Physicians, Hawthorne, NY, USA.; Pisapia JM; Department of Neurosurgery and Department of Pediatrics, Westchester Medical Center, 100 Woods Road, Taylor Pavilion E135, Valhalla, NY, 10595, USA.; Department of Neurosurgery, New York Medical College, Valhalla, NY, 10595, USA.; Wolf SM; Department of Pediatric Neurology, Boston Children's Health Physicians, Hawthorne, NY, USA.; Department of Neurology, New York Medical College, Valhalla, NY, USA.
Source
Publisher: Springer International Country of Publication: Germany NLM ID: 8503227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-0350 (Electronic) Linking ISSN: 02567040 NLM ISO Abbreviation: Childs Nerv Syst Subsets: MEDLINE
Subject
Language
English
Abstract
Purpose: Stereoelectroencephalography (SEEG) is a diagnostic surgery that implants electrodes to identify areas of epileptic onset in patients with drug-resistant epilepsy (DRE). SEEG is effective in identifying the epileptic zone; however, placement of electrodes in very young children has been considered contraindicated due to skull thinness. The goal of this study was to evaluate if SEEG is safe and accurate in young children with thin skulls.
Methods: Four children under the age of two years old with DRE underwent SEEG to locate the region of seizure onset. Presurgical planning and placement of electrodes were performed using ROSA One Brain. Preoperative electrode plans were merged with postoperative CT scans to determine accuracy. Euclidean distance between the planned and actual trajectories was calculated using a 3D coordinate system at both the entry and target points for each electrode.
Results: Sixty-three electrodes were placed among four patients. Mean skull thickness at electrode entry sites was 2.34 mm. The mean difference between the planned and actual entry points was 1.12 mm, and the mean difference between the planned and actual target points was 1.73 mm. No significant correlation was observed between planned and actual target points and skull thickness (Pearson R = - 0.170). No perioperative or postoperative complications were observed.
Conclusions: This study demonstrates that SEEG can be safe and accurate in children under two years of age despite thin skulls. SEEG should be considered for young children with DRE, and age and skull thickness are not definite contraindications to the surgery.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Methods: Four children under the age of two years old with DRE underwent SEEG to locate the region of seizure onset. Presurgical planning and placement of electrodes were performed using ROSA One Brain. Preoperative electrode plans were merged with postoperative CT scans to determine accuracy. Euclidean distance between the planned and actual trajectories was calculated using a 3D coordinate system at both the entry and target points for each electrode.
Results: Sixty-three electrodes were placed among four patients. Mean skull thickness at electrode entry sites was 2.34 mm. The mean difference between the planned and actual entry points was 1.12 mm, and the mean difference between the planned and actual target points was 1.73 mm. No significant correlation was observed between planned and actual target points and skull thickness (Pearson R = - 0.170). No perioperative or postoperative complications were observed.
Conclusions: This study demonstrates that SEEG can be safe and accurate in children under two years of age despite thin skulls. SEEG should be considered for young children with DRE, and age and skull thickness are not definite contraindications to the surgery.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)