학술논문
Prevalence and determinants of osteoporosis in Congolese patients with axial rheumatism: a cross-sectional hospital-based study.
Document Type
Academic Journal
Author
Mavinga A; Rheumatology Unit, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo.; Mbuyi J; Rheumatology Unit, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo.; Matanda D; Rheumatology Unit, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo.; Lebughe P; Rheumatology Unit, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo.; Mulumba JC; Rheumatology Unit, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo.; Nyembue V; Internal Medicine Unit, Sino-Congolese Friendship Hospital, Brazzaville, Congo.; Lukusa A; Internal Medicine Unit, Ngaliema Clinic, Kinshasa, Democratic Republic of Congo.; Divengi JP; Internal Medicine Unit, Provincial General Hospital of Kinshasa, Kinshasa, Democratic Republic of Congo.; Lusiensie T; Internal Medicine Unit, Provincial General Hospital of Kinshasa, Kinshasa, Democratic Republic of Congo.; Mbuyi-Muamba JM; Rheumatology Unit, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo.; Malemba JJ; Rheumatology Unit, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Source
Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE
Subject
Language
English
Abstract
Introduction: osteoporosis seems to be uncommon in sub-Saharan Africa. The aim of this study was to determine prevalence and determinants of osteoporosis in Congolese outpatients attending rheumatology consultation for axial rheumatism in Kinshasa, Democratic Republic of the Congo.
Methods: a cross-sectional hospital-based study from January to December 2018 among outpatients received for axial rheumatism in 8 hospitals of Kinshasa. The parameters of interest were age, sex, body mass index (BMI), alcoholism, smoking, physical activity, sunlight exposure, intake of dairy products, the notion of personal or parental fracture, a bone mineral density (BMD) and a phosphocalcic metabolism. The BMD was measured by using the dual energy X-ray absorptiométry. Serum level of calcium, Vitamin D, phosphore and parathormon were determined to assess the phosphocalcic metabolism. Osteoporosis was defined by a T-Score ≤ -2.5 SD. Standard statistical tests were used to analyze the results.
Results: ninety patients (75 women and 15 men) were included. Their mean age was 63.5 ± 12.2 years. Low back pain 71.1% (n=63) was the main symptom. The rate of patients with osteoporosis, osteopenia, and normal bone density was 34.4% (n=31), 43.9% (n=44), and 16.7% (n=15) respectively. Pathological bone fractures were not noted. Ageing (aOR: 1.31, IC95%: 1.11-1.54; p=0.002), smoking (aOR: 14.65, IC95%: 1.38-156.1; p=0.045) and non-obese status (aOR: 32.3, IC95% 1.50-696; p=0.032) were identified as determinants of osteoporosis.
Conclusion: in the present study, osteoporosis is common in Congolese patients with axial pain and is more frequent in women. Its determinants are ageing, smoking and non-obese status.
Competing Interests: The authors declare no competing interests.
(Copyright: Aldo Mavinga et al.)
Methods: a cross-sectional hospital-based study from January to December 2018 among outpatients received for axial rheumatism in 8 hospitals of Kinshasa. The parameters of interest were age, sex, body mass index (BMI), alcoholism, smoking, physical activity, sunlight exposure, intake of dairy products, the notion of personal or parental fracture, a bone mineral density (BMD) and a phosphocalcic metabolism. The BMD was measured by using the dual energy X-ray absorptiométry. Serum level of calcium, Vitamin D, phosphore and parathormon were determined to assess the phosphocalcic metabolism. Osteoporosis was defined by a T-Score ≤ -2.5 SD. Standard statistical tests were used to analyze the results.
Results: ninety patients (75 women and 15 men) were included. Their mean age was 63.5 ± 12.2 years. Low back pain 71.1% (n=63) was the main symptom. The rate of patients with osteoporosis, osteopenia, and normal bone density was 34.4% (n=31), 43.9% (n=44), and 16.7% (n=15) respectively. Pathological bone fractures were not noted. Ageing (aOR: 1.31, IC95%: 1.11-1.54; p=0.002), smoking (aOR: 14.65, IC95%: 1.38-156.1; p=0.045) and non-obese status (aOR: 32.3, IC95% 1.50-696; p=0.032) were identified as determinants of osteoporosis.
Conclusion: in the present study, osteoporosis is common in Congolese patients with axial pain and is more frequent in women. Its determinants are ageing, smoking and non-obese status.
Competing Interests: The authors declare no competing interests.
(Copyright: Aldo Mavinga et al.)