학술논문
Multisensory Integration: Is Medial Prefrontal Cortex Signaling Relevant for the Treatment of Higher-Order Visual Dysfunctions?
Document Type
Academic Journal
Author
Skirzewski M; Rodent Cognition Research and Innovation Core, University of Western Ontario, London, ON, Canada.; Molotchnikoff S; Département de Sciences Biologiques, Université de Montréal, Montreal, QC, Canada.; Département de Génie Electrique et Génie Informatique, Université de Sherbrooke, Sherbrooke, QC, Canada.; Hernandez LF; Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, United States.; Maya-Vetencourt JF; Department of Biology, University of Pisa, Pisa, Italy.; Centre for Synaptic Neuroscience, Istituto Italiano di Tecnologia (IIT), Genova, Italy.
Source
Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477914 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5099 (Print) Linking ISSN: 16625099 NLM ISO Abbreviation: Front Mol Neurosci Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
1662-5099
Abstract
In the mammalian brain, information processing in sensory modalities and global mechanisms of multisensory integration facilitate perception. Emerging experimental evidence suggests that the contribution of multisensory integration to sensory perception is far more complex than previously expected. Here we revise how associative areas such as the prefrontal cortex, which receive and integrate inputs from diverse sensory modalities, can affect information processing in unisensory systems via processes of down-stream signaling. We focus our attention on the influence of the medial prefrontal cortex on the processing of information in the visual system and whether this phenomenon can be clinically used to treat higher-order visual dysfunctions. We propose that non-invasive and multisensory stimulation strategies such as environmental enrichment and/or attention-related tasks could be of clinical relevance to fight cerebral visual impairment.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2022 Skirzewski, Molotchnikoff, Hernandez and Maya-Vetencourt.)
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2022 Skirzewski, Molotchnikoff, Hernandez and Maya-Vetencourt.)