학술논문
Meeting report: transposable elements at the crossroads of evolution, health and disease 2023.
Document Type
Academic Journal
Author
Arkhipova IR; Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, MA, 02543, USA. iarkhipova@mbl.edu.; Burns KH; Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA.; Chiappinelli KB; Department of Microbiology, Immunology and Tropical Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, 20052, USA.; Chuong EB; BioFrontiers Institute and Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, CO, 80309, USA.; Goubert C; McGill Genome Centre, Department of Human Genomics, Canadian Centre for Computational Genomics, McGill University, Montréal, Canada.; Department of Pharmacy Practice & Science, University of Arizona, Tucson, AZ, 85721, USA.; Guarné A; Department of Biochemistry and Centre de Recherche en Biologie Structurale, McGill University, Montreal, QC, H3G 0B1, Canada.; Larracuente AM; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; Lee EA; Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.; Levin HL; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.
Source
Publisher: BioMed Central Country of Publication: England NLM ID: 101519891 Publication Model: Electronic Cited Medium: Print ISSN: 1759-8753 (Print) NLM ISO Abbreviation: Mob DNA Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
1759-8753
Abstract
The conference "Transposable Elements at the Crossroads of Evolution, Health and Disease" was hosted by Keystone Symposia in Whistler, British Columbia, Canada, on September 3-6, 2023, and was organized by Kathleen Burns, Harmit Malik and Irina Arkhipova. The central theme of the meeting was the incredible diversity of ways in which transposable elements (TEs) interact with the host, from disrupting the existing genes and pathways to creating novel gene products and expression patterns, enhancing the repertoire of host functions, and ultimately driving host evolution. The meeting was organized into six plenary sessions and two afternoon workshops with a total of 50 invited and contributed talks, two poster sessions, and a career roundtable. The topics ranged from TE roles in normal and pathological processes to restricting and harnessing TE activity based on mechanistic insights gained from genetic, structural, and biochemical studies.
(© 2023. The Author(s).)
(© 2023. The Author(s).)