학술논문

Establishing Sickle Cell Disease Stroke Prevention Teams in Africa is Feasible: Program Evaluation Using the RE-AIM Framework.
Document Type
Academic Journal
Author
Ghafuri DL; Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease.; Abdullahi SU; Departments of Pediatrics.; Dambatta AH; Radiology.; Galadanci J; Department of Computer Science, Bayero University.; Tabari MA; Departments of Radiology.; Bello-Manga H; Hematology and Blood Transfusion.; Idris N; Departments of Radiology.; Inuwa H; Departments of Pediatrics.; Tijjani A; Departments of Pediatrics.; Suleiman AA; Departments of Radiology.; Jibir BW; Pediatrics, Murtala Mohammed Specialist Hospital.; Gambo S; Pediatrics, Murtala Mohammed Specialist Hospital.; Gambo AI; Pediatrics, Murtala Mohammed Specialist Hospital.; Khalifa Y; Department of Administration, Aminu Kano Teaching Hospital, Kano.; Haliru L; Department of Pediatrics, Barau Dikko Teaching Hospital/Kaduna State University, Kaduna, Nigeria.; Abdulrasheed S; Department of Pediatrics, Barau Dikko Teaching Hospital/Kaduna State University, Kaduna, Nigeria.; Zakari MA; Histopathology, Bayero University/Aminu Kano Teaching Hospital.; Greene BC; Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease.; Trevathan E; Department of Neurology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN.; Jordan LC; Department of Pediatrics, Division of Pediatric Neurology.; Aliyu MH; Health Policy, Vanderbilt Institute for Global Health, Vanderbilt University Medical Center.; Baumann AA; Brown School of Social Work, Washington University of St. Louis, St. Louis, MO.; DeBaun MR; Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease.
Source
Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505928 Publication Model: Print Cited Medium: Internet ISSN: 1536-3678 (Electronic) Linking ISSN: 10774114 NLM ISO Abbreviation: J Pediatr Hematol Oncol Subsets: MEDLINE
Subject
Language
English
Abstract
We used the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework to evaluate a Stroke Prevention Team's readiness to prevent strokes in children with sickle cell anemia living in northern Nigeria. The NIH sponsored Stroke Prevention Trial in Nigeria included a goal of a sustainable stroke prevention program. The program's 1-year reach for transcranial Doppler screening was 14.7% (4710/32,000) of which 6.0% (281/4710) had abnormal velocities (≥200 cm/s). All participants with abnormal transcranial Doppler velocities were started on hydroxyurea (effectiveness). The leaders of all 5 hospitals agreed to adopt the program. After 1 year, program-implementation and maintenance rates were 100%, demonstrating the program's feasibility and short-term sustainability.
Competing Interests: M.R.D.: had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. M.R.D.: designed the study. S.U.A. and M.A.T.: provided the TCD training. A.H.D., H.B.-M., H.I., A.T., A.A.S., B.W.J., S.G., Y.K., L.H., S.A., M.A.Z., and N.I.: administered the TCD screening. E.T. and L.J.: verified the neurological examinations. A.I.G., F.M.U., M.A.T., A.I.G., S.U.A., B.C.G., J.G., and D.L.G.: collected the data. D.L.G. and M.R.: performed the analyses. M.R.D., S.A., D.L.G., A.A.B., M.R.D.: interpreted the results. D.L.G., A.A.B., L.C.J., E.T., M.H.A., and M.R.D.: wrote the manuscript. Before submission, all authors reviewed the manuscript.The authors declare no conflict of interest.
(Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc.)