학술논문

Orbital invasion by ACTH-secreting pituitary adenomas.
Document Type
Academic Journal
Author
Dhaliwal JS; University of Colorado School of Medicine, Aurora, Colorado, U.S.A.; †Department of Ophthalmology, University of Colorado Eye Center, Aurora, Colorado, U.S.A.; ‡Department of Neurosurgery, School of Medicine, University of Colorado Denver, Aurora, Colorado, U.S.A; and §South Denver Neurosurgery, Denver, Colorado, U.S.A.; Seibold LKKleinschmidt-Demasters BKLillehei KOHink EMPrall JADurairaj VD
Source
Publisher: Lippincott Williams & Wilkins for the American Society of Ophthalmic Plastic and Reconstructive Surgery Country of Publication: United States NLM ID: 8508431 Publication Model: Print Cited Medium: Internet ISSN: 1537-2677 (Electronic) Linking ISSN: 07409303 NLM ISO Abbreviation: Ophthalmic Plast Reconstr Surg Subsets: MEDLINE
Subject
Language
English
Abstract
Orbital invasion by pituitary tumors is rare. To the best of the authors' knowledge, adrenocorticotrophin (ACTH)-secreting pituitary tumors with orbital invasion have not been described in MEDLINE indexed literature. The authors report 2 cases of ACTH-secreting tumors with orbital invasion. One patient had a history of endoscopic transsphenoidal subtotal resection of an ACTH-secreting tumor and presented with recurrence in the orbit. The second patient had a long history of visual loss considered to be secondary to glaucoma. Neuroimaging revealed a destructive mass involving the sella turcica with extension in the right orbit. Debulking of the mass was performed via a transsphenoidal approach, and histopathology revealed an ACTH-secreting adenoma. ACTH-secreting adenoma should be considered in the differential of tumors involving the sella turcica with orbital invasion.