학술논문
Ninety-day outcomes in patients diagnosed with COVID-19 in São Paulo, Brazil: a cohort study.
Document Type
Academic Journal
Author
Fumis RRL; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Costa ELV; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Departamento Cardiopulmonar, Divisão de Pneumologia, Instituto do Coração - InCor - Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.; Tomazini BM; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; HCor Research Institute, São Paulo (SP) Brasil.; Taniguchi LU; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Serviço de Emergência, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.; Costa LDV; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Morinaga CV; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Sá MMSE; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Azevedo LCP; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Serviço de Emergência, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.; Nascimento TC; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Ledo CB; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Oliveira MS; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Cardoso LF; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Pastore Junior L; Hospital Sírio-Libanês, São Paulo (SP) Brasil.; Vieira Junior JM; Hospital Sírio-Libanês, São Paulo (SP) Brasil.
Source
Publisher: Sociedade Brasileira de Pneumologia e Tisilogia Country of Publication: Brazil NLM ID: 101222274 Publication Model: eCollection Cited Medium: Internet ISSN: 1806-3756 (Electronic) Linking ISSN: 18063713 NLM ISO Abbreviation: J Bras Pneumol Subsets: MEDLINE
Subject
Language
English; Portuguese
Abstract
Objective: COVID-19 has been associated with a significant burden to those who survive the acute phase. We aimed to describe the quality of life and symptoms of anxiety, depression, and posttraumatic stress disorder (PTSD) at 90 days after hospital discharge of COVID-19 patients.
Methods: Patients with COVID-19 admitted to a private hospital in the city of São Paulo, Brazil, between April of 2020 and April of 2021 were interviewed by telephone at 30 and 90 days after discharge to assess the quality of life and symptoms of depression, anxiety, and PTSD.
Results: A total of 2,138 patients were included. The mean age was 58.6 ± 15.8 years, and the median length of hospital stay was 9.0 (5.0-15.8) days. Between the two time points, depression increased from 3.1% to 7.2% (p < 0.001), anxiety increased from 3.2% to 6.2% (p < 0.001), and PTSD increased from 2.3% to 5.0% (p < 0.001). At least one physical symptom related to COVID-19 diagnosis persisted in 32% of patients at day 90.
Conclusions: Persistence of physical symptoms was high even at 90 days after discharge. Although the prevalence of symptoms of anxiety, depression, and PTSD was low, these symptoms persisted for three months, with a significant increase between the time points. This finding indicates the need to identify at-risk patients so that they can be given an appropriate referral at discharge.
Methods: Patients with COVID-19 admitted to a private hospital in the city of São Paulo, Brazil, between April of 2020 and April of 2021 were interviewed by telephone at 30 and 90 days after discharge to assess the quality of life and symptoms of depression, anxiety, and PTSD.
Results: A total of 2,138 patients were included. The mean age was 58.6 ± 15.8 years, and the median length of hospital stay was 9.0 (5.0-15.8) days. Between the two time points, depression increased from 3.1% to 7.2% (p < 0.001), anxiety increased from 3.2% to 6.2% (p < 0.001), and PTSD increased from 2.3% to 5.0% (p < 0.001). At least one physical symptom related to COVID-19 diagnosis persisted in 32% of patients at day 90.
Conclusions: Persistence of physical symptoms was high even at 90 days after discharge. Although the prevalence of symptoms of anxiety, depression, and PTSD was low, these symptoms persisted for three months, with a significant increase between the time points. This finding indicates the need to identify at-risk patients so that they can be given an appropriate referral at discharge.