학술논문
Safety and Short-Term Outcomes for Infants < 2.5 kg Undergoing PDA Device Closure: A C3PO Registry Study.
Document Type
Academic Journal
Author
Barry OM; Division of Pediatric Cardiology, New York-Presbyterian - Morgan Stanley Children's Hospital, Columbia University Medical Center, 3959 Broadway, CHN-253, New York, NY, 10032, USA. omb2104@cumc.columbia.edu.; Gudausky TM; Division of Pediatric Cardiology, Medical College of Wisconsin and Herma Heart Institute at Children's Wisconsin, Milwaukee, WI, USA.; Balzer DT; St. Louis Children's Hospital, St. Louis, MO, USA.; Bocks ML; UH Rainbow Babies Hospital, Cleveland, OH, USA.; Boe BA; Nationwide Children's Hospital, Columbus, OH, USA.; Callahan R; Boston Children's Hospital, Boston, MA, USA.; El-Said H; Rady Children's Hospital -San Diego, San Diego, CA, USA.; Farias MJ; Arnold Palmer Children's Hospital, Orlando, FL, USA.; Foerster S; Division of Pediatric Cardiology, Medical College of Wisconsin and Herma Heart Institute at Children's Wisconsin, Milwaukee, WI, USA.; Goldstein BH; Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.; Holzer RJ; Weill Cornell, New York, NY, USA.; Janssen D; Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.; Levy P; Boston Children's Hospital, Boston, MA, USA.; O'Byrne ML; The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Rahman G; Boston Children's Hospital, Boston, MA, USA.; Sathanandam S; Le Bonheur Children's Hospital, Memphis, TN, USA.; Shahanavaz S; Cincinnati Children's Hospital, Cincinnati, OH, USA.; Whiteside W; University of Michigan, Ann Arbor, MI, USA.; Turner ME; Division of Pediatric Cardiology, New York-Presbyterian - Morgan Stanley Children's Hospital, Columbia University Medical Center, 3959 Broadway, CHN-253, New York, NY, 10032, USA.
Source
Publisher: Springer Verlag Country of Publication: United States NLM ID: 8003849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1971 (Electronic) Linking ISSN: 01720643 NLM ISO Abbreviation: Pediatr Cardiol Subsets: MEDLINE
Subject
Language
English
Abstract
To evaluate short-term procedural outcomes and safety for infants < 2.5 kg who underwent catheterization with intended patent ductus arteriosus (PDA) device closure in a multi-center registry, as performance of this procedure becomes widespread. A multi-center retrospective review was performed using data from the Congenital Cardiac Catheterization Project on Outcomes (C3PO) registry. Data were collected for all intended cases of PDA closure in infants < 2.5 kg from April 2019 to December 2020 at 13 participating sites. Successful device closure was defined as device placement at the conclusion of the catheterization. Procedural outcomes and adverse events (AE) were described, and associations between patient characteristics, procedural outcomes and AEs were analyzed. During the study period, 300 cases were performed with a median weight of 1.0 kg (range 0.7-2.4). Successful device closure was achieved in 98.7% of cases with a 1.7% incidence of level 4/5 AEs, including one periprocedural mortality. Neither failed device placement nor adverse events were significantly associated with patient age, weight or institutional volume. Higher incidence of adverse events associated with patients who had non-cardiac problems (p = 0.017) and cases with multiple devices attempted (p = 0.064). Transcatheter PDA closure in small infants can be performed with excellent short-term outcomes and safety across institutions with variable case volume.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)