학술논문
Is non-contrast MRI sufficient to detect meningioma residue after surgery?
Document Type
Academic Journal
Author
Alonso SM; Radiology 2 Department, Strasbourg University Hospital, Hautepierre Hospital, Strasbourg, France. Electronic address: sophie.motillonalonso@yahoo.fr.; Lersy F; Radiology 2 Department, Strasbourg University Hospital, Hautepierre Hospital, Strasbourg, France.; Ardellier FD; Radiology 2 Department, Strasbourg University Hospital, Hautepierre Hospital, Strasbourg, France; Engineering science, computer science and imaging laboratory (ICube), Integrative Multimodal Imaging in Healthcare, UMR 7357, University of Strasbourg-CNRS, Strasbourg, France.; Cebula H; Engineering science, computer science and imaging laboratory (ICube), Integrative Multimodal Imaging in Healthcare, UMR 7357, University of Strasbourg-CNRS, Strasbourg, France; Neurosurgery Department, Strasbourg University Hospital, Hautepierre Hospital, Strasbourg, France.; Proust F; Engineering science, computer science and imaging laboratory (ICube), Integrative Multimodal Imaging in Healthcare, UMR 7357, University of Strasbourg-CNRS, Strasbourg, France; Neurosurgery Department, Strasbourg University Hospital, Hautepierre Hospital, Strasbourg, France.; Onofrei A; Radiology 2 Department, Strasbourg University Hospital, Hautepierre Hospital, Strasbourg, France.; Chammas A; Radiology 2 Department, Strasbourg University Hospital, Hautepierre Hospital, Strasbourg, France.; Kremer S; Radiology 2 Department, Strasbourg University Hospital, Hautepierre Hospital, Strasbourg, France; Engineering science, computer science and imaging laboratory (ICube), Integrative Multimodal Imaging in Healthcare, UMR 7357, University of Strasbourg-CNRS, Strasbourg, France.
Source
Publisher: Masson Country of Publication: France NLM ID: 7705086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0150-9861 (Print) Linking ISSN: 01509861 NLM ISO Abbreviation: J Neuroradiol Subsets: MEDLINE
Subject
Language
English
ISSN
0150-9861
Abstract
Background: Contrast-enhanced magnetic resonance imaging (MRI) is the imaging modality routinely used to follow up patients who have undergone surgical resection of brain meningiomas. There are growing concerns about the massive use of gadolinium-based contrast agents (GBCA). Our aim was to evaluate the performance of a new imaging protocol, performed without GBCA injection, in the detection of tumoral residue or local recurrence after surgery of parafalcine and convexity meningiomas.
Materials and Methods: Only adult patients with a documented resected parafalcine or convexity meningioma were included. We performed a dedicated MRI protocol that included non-contrast and post-contrast sequences. The presence or absence of residue on the unenhanced sequences was independently recorded by three observers: first blindly, then in comparison with a baseline enhanced MRI examination.
Results: A total of 51 patients were included. 37 of them featured a tumor residue on the reference enhanced sequence. Overall, an average of 32 of 37 (87%) residues were identified on the unenhanced sequences that were blindly reviewed; and more than 34 of 37 (93%) were identified with the help of the comparative baseline enhanced examination, with a high sensitivity. The missed cases were related to small residues.
Conclusion: Unenhanced MRI sequences are highly sensitive and specific in identifying a tumor residue or a local recurrence in the post operative follow up of brain meningiomas. Sensitivity is even higher with the help of a comparative baseline enhanced MRI examination, whatever the strength of magnetic field.
Competing Interests: Declaration of Competing Interest The Authors declare that there is no conflict of interest.
(Copyright © 2023 Elsevier Masson SAS. All rights reserved.)
Materials and Methods: Only adult patients with a documented resected parafalcine or convexity meningioma were included. We performed a dedicated MRI protocol that included non-contrast and post-contrast sequences. The presence or absence of residue on the unenhanced sequences was independently recorded by three observers: first blindly, then in comparison with a baseline enhanced MRI examination.
Results: A total of 51 patients were included. 37 of them featured a tumor residue on the reference enhanced sequence. Overall, an average of 32 of 37 (87%) residues were identified on the unenhanced sequences that were blindly reviewed; and more than 34 of 37 (93%) were identified with the help of the comparative baseline enhanced examination, with a high sensitivity. The missed cases were related to small residues.
Conclusion: Unenhanced MRI sequences are highly sensitive and specific in identifying a tumor residue or a local recurrence in the post operative follow up of brain meningiomas. Sensitivity is even higher with the help of a comparative baseline enhanced MRI examination, whatever the strength of magnetic field.
Competing Interests: Declaration of Competing Interest The Authors declare that there is no conflict of interest.
(Copyright © 2023 Elsevier Masson SAS. All rights reserved.)