학술논문
Response to direct-acting antivirals for hepatitis C treatment in vertically HIV/HCV co-infected patients.
Document Type
Academic Journal
Author
Carrasco I; Hospital General Universitario Gregorio Marañón and Gregorio Marañón Research Institute (IiSGM), Madrid, Spain.; Universidad Complutense de Madrid, Madrid, Spain.; Sainz T; Hospital Universitario La Paz and La Paz Research Institute (IdiPAZ), Madrid, Spain.; Frick MA; Hospital Vall d'Hebron, Barcelona, Spain.; Jiménez de Ory S; Hospital General Universitario Gregorio Marañón and Gregorio Marañón Research Institute (IiSGM), Madrid, Spain.; Fortuny C; Hospital Sant Joan de Déu, Barcelona, Spain.; Burgos J; Hospital Vall d'Hebron, Barcelona, Spain.; Montero M; Hospital Universitario y Politécnico de La Fe, Valencia, Spain.; Gavilán C; Hospital San Juan de Alicante, Sant Joan d'Alacant, Spain.; Falcón MD; Hospital Virgen del Rocío, Sevilla, Spain.; Couceiro JA; Complejo Hospitalario de Pontevedra, Pontevedra, Spain.; Bernardino JI; Hospital Universitario La Paz and La Paz Research Institute (IdiPAZ), Madrid, Spain.; Bisbal O; Hospital 12 de Octubre, Madrid, Spain.; Guerrero C; Hospital Miguel Servet, Zaragoza, Spain.; Aldámiz-Echevarría MT; Hospital General Universitario Gregorio Marañón and Gregorio Marañón Research Institute (IiSGM), Madrid, Spain.; Berenguer J; Hospital General Universitario Gregorio Marañón and Gregorio Marañón Research Institute (IiSGM), Madrid, Spain.; Navarro ML; Hospital General Universitario Gregorio Marañón and Gregorio Marañón Research Institute (IiSGM), Madrid, Spain.; Universidad Complutense de Madrid, Madrid, Spain.
Source
Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9435672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2893 (Electronic) Linking ISSN: 13520504 NLM ISO Abbreviation: J Viral Hepat Subsets: MEDLINE
Subject
Language
English
Abstract
Direct-acting antivirals (DAAs) for HCV treatment have improved tolerance and efficacy among adults, but experience in vertical transmission is scarce. In our vertically HIV/HCV co-infected youth cohort of 58 patients, DAA achieved excellent rates of cure among naïve and pretreated individuals. Treating vertically infected seems important as 29.6% displayed advanced fibrosis at treatment initiation.
(© 2020 John Wiley & Sons Ltd.)
(© 2020 John Wiley & Sons Ltd.)