학술논문

Uncovering the genomic toll of the Black Death.
Document Type
Academic Journal
Author
Kuiper J; Department of Ophthalmology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands; Center for Translational Immunology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.; van Endert P; Université Paris Cité, INSERM, CNRS, Institut Necker Enfants Malades, F-75015 Paris, France. Electronic address: peter.van-endert@inserm.fr.
Source
Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4981 (Electronic) Linking ISSN: 14714906 NLM ISO Abbreviation: Trends Immunol Subsets: MEDLINE
Subject
Language
English
Abstract
The Black Death, a notorious devastating pandemic caused by Yersinia pestis infection during the 14th century, posed a formidable challenge to human immune defenses. A new article by Klunk et al. reports that a variant in an antigen-processing gene may have favored survival during the plague and may have undergone genomic selection in Europeans at unprecedented speed.
Competing Interests: Declaration of interests No interests are declared.
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