학술논문
Factors Predicting Ictal Quality in Bilateral Electroconvulsive Therapy Sessions.
Document Type
Academic Journal
Author
de Arriba-Arnau A; Neurosciences Group-Psychiatry and Mental Health, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Department of Psychiatry, Hospital Universitari de Bellvitge-ICS, 08907 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Carlos III Health Institute, 28029 Madrid, Spain.; Dalmau Llitjos A; Department of Anesthesiology, Reanimation and Pain Clinic, Bellvitge University Hospital-ICS, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.; Department of Clinical Sciences, School of Medicine, Faculty of Medicine and Health Sciences, Campus Bellvitge, Universitat de Barcelona (UB), 08907 Barcelona, Spain.; Soria V; Neurosciences Group-Psychiatry and Mental Health, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Department of Psychiatry, Hospital Universitari de Bellvitge-ICS, 08907 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Carlos III Health Institute, 28029 Madrid, Spain.; Department of Clinical Sciences, School of Medicine, Faculty of Medicine and Health Sciences, Campus Bellvitge, Universitat de Barcelona (UB), 08907 Barcelona, Spain.; Savino S; Department of Anesthesiology, Reanimation and Pain Clinic, Bellvitge University Hospital-ICS, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.; Salvat-Pujol N; Neurosciences Group-Psychiatry and Mental Health, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Department of Psychiatry, Hospital Universitari de Bellvitge-ICS, 08907 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Carlos III Health Institute, 28029 Madrid, Spain.; Department of Mental Health, Corporació Sanitària Parc Taulí, 08208 Sabadell, Spain.; Curto J; Department of Public Health, Mental Health and Perinatal Nursing, School of Nursing, Faculty of Medicine and Health Sciences, Campus Bellvitge, Universitat de Barcelona (UB), 08907 Barcelona, Spain.; Menchón JM; Neurosciences Group-Psychiatry and Mental Health, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Department of Psychiatry, Hospital Universitari de Bellvitge-ICS, 08907 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Carlos III Health Institute, 28029 Madrid, Spain.; Department of Clinical Sciences, School of Medicine, Faculty of Medicine and Health Sciences, Campus Bellvitge, Universitat de Barcelona (UB), 08907 Barcelona, Spain.; Urretavizcaya M; Neurosciences Group-Psychiatry and Mental Health, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Department of Psychiatry, Hospital Universitari de Bellvitge-ICS, 08907 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Carlos III Health Institute, 28029 Madrid, Spain.; Department of Clinical Sciences, School of Medicine, Faculty of Medicine and Health Sciences, Campus Bellvitge, Universitat de Barcelona (UB), 08907 Barcelona, Spain.
Source
Publisher: MDPI Country of Publication: Switzerland NLM ID: 101598646 Publication Model: Electronic Cited Medium: Print ISSN: 2076-3425 (Print) Linking ISSN: 20763425 NLM ISO Abbreviation: Brain Sci Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2076-3425
Abstract
In electroconvulsive therapy (ECT), ictal characteristics predict treatment response and can be modified by changes in seizure threshold and in the ECT technique. We aimed to study the impact of ECT procedure-related variables that interact during each session and might influence the seizure results. Two hundred and fifty sessions of bilateral ECT in forty-seven subjects were included. Seizure results were evaluated by two different scales of combined ictal EEG parameters (seizure quality index (SQI) and seizure adequacy markers sum (SAMS) scores) and postictal suppression rating. Repeated measurement regression analyses were performed to identify predictors of each session's three outcome variables. Univariate models identified age, physical status, hyperventilation, basal oxygen saturation, days between sessions, benzodiazepines, lithium, and tricyclic antidepressants as predictors of seizure quality. Days elapsed between sessions, higher oxygen saturation and protocolized hyperventilation application were significant predictors of better seizure quality in both scales used in multivariate models. Additionally, lower ASA classification influenced SQI scores as well as benzodiazepine use and lithium daily doses were predictors of SAMS scores. Higher muscle relaxant doses and lower applied stimulus intensities significantly influenced the postictal suppression rating. The study found several modifiable procedural factors that impacted the obtained seizure characteristics; they could be adjusted to optimize ECT session results.