학술논문
HOMBRE: A Trial Comparing 2 Weight Loss Approaches for Latino Men.
Document Type
Academic Journal
Author
Rosas LG; Department of Epidemiology & Population Health, School of Medicine, Stanford University, Palo Alto, California. Electronic address: lgrosas@stanford.edu.; Lv N; Department of Medicine, University of Illinois Chicago, Chicago, Illinois; Institute of Health Research and Policy, University of Illinois Chicago, Chicago, Illinois.; Xiao L; Department of Epidemiology & Population Health, School of Medicine, Stanford University, Palo Alto, California.; Venditti EM; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Lewis MA; RTI Center for Communications Science, RTI International, Seattle, Washington.; Azar KMJ; Sutter Health, Sutter Health Center for Health Systems Research, Palo Alto, California.; Hooker SP; College of Health and Human Services, San Diego State University, San Diego, California.; Zavella P; Latin American and Latino Studies department, University of California Santa Cruz, Santa Cruz, California.; Ma J; Department of Medicine, University of Illinois Chicago, Chicago, Illinois; Institute of Health Research and Policy, University of Illinois Chicago, Chicago, Illinois.
Source
Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8704773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2607 (Electronic) Linking ISSN: 07493797 NLM ISO Abbreviation: Am J Prev Med Subsets: MEDLINE
Subject
Language
English
Abstract
Introduction: Latino men have been drastically under-represented in research to identify effective behavioral weight-loss interventions. This trial compared 2 interventions for weight loss: (1) a culturally adapted intervention (HOMBRE) and (2) a minimal-intensity intervention.
Study Design: Randomized controlled trial.
Setting/participants: Latino men with a BMI ≥27 kg/m2 and 1 or more cardiometabolic risk factors (N=424) were recruited (February 15, 2017‒October 2, 2018) from 14 medical centers and randomized to receive 1 of the 2 interventions.
Intervention: HOMBRE provided men a choice among 3 options: coach-facilitated group sessions using online video conferencing, coach-facilitated group sessions in person, and prerecorded videos of group sessions available online.
Main Outcome Measures: The primary outcome was the proportion of participants sustaining clinically significant (≥5% of baseline) weight loss at 18 months. Secondary outcomes included weight loss trajectory over time, 3% and 10% weight loss, cardiometabolic risk factors, health behaviors, and psychosocial well-being at baseline and 18 months. Data were analyzed from October 6, 2020 to January 15, 2022.
Results: Participants were predominantly middle aged (47.0 [SD=11.9] years), were married (74.3%), were with at least some college experience (79.7%), and had middle to upper incomes (72.4% with annual family incomes >$75,000). Their average BMI was 33.1 kg/m2 (SD=5.1). The proportion achieving clinically significant weight loss at 18 months was 27.4% in the HOMBRE intervention and 20.6% in the minimal-intensity intervention (mean difference=7.2%, 95% CI= -1.8, 17.0; p=0.13). Mean difference between the HOMBRE vs the minimal-intensity group was ‒1.25 kg at 6 months (95% CI= -2.28, -0.21; p=0.02) and ‒1.11 kg at 12 months (95% CI= -2.11, -0.10; p=0.03) using weight measurement data abstracted from the Electronic Health Record and by self report. There were no significant differences in secondary outcomes.
Conclusions: Among Latino men with overweight and obesity, HOMBRE was not more effective for clinically significant weight loss than a minimal-intensity intervention at 18 months.
(Copyright © 2022 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.)
Study Design: Randomized controlled trial.
Setting/participants: Latino men with a BMI ≥27 kg/m
Intervention: HOMBRE provided men a choice among 3 options: coach-facilitated group sessions using online video conferencing, coach-facilitated group sessions in person, and prerecorded videos of group sessions available online.
Main Outcome Measures: The primary outcome was the proportion of participants sustaining clinically significant (≥5% of baseline) weight loss at 18 months. Secondary outcomes included weight loss trajectory over time, 3% and 10% weight loss, cardiometabolic risk factors, health behaviors, and psychosocial well-being at baseline and 18 months. Data were analyzed from October 6, 2020 to January 15, 2022.
Results: Participants were predominantly middle aged (47.0 [SD=11.9] years), were married (74.3%), were with at least some college experience (79.7%), and had middle to upper incomes (72.4% with annual family incomes >$75,000). Their average BMI was 33.1 kg/m
Conclusions: Among Latino men with overweight and obesity, HOMBRE was not more effective for clinically significant weight loss than a minimal-intensity intervention at 18 months.
(Copyright © 2022 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.)