학술논문
Reproducibility of asystole during head-up tilt testing in patients with neurally mediated syncope.
Document Type
Academic Journal
Author
Foglia-Manzillo G; Department of Cardiology, Ospedale Valduce, Como, Italy. cardiologia@valduce.it; Romanò M; Corrado G; Tagliagambe LM; Tadeo G; Spata M; Spinelli A; Grieco A; Santarone M
Source
Publisher: Oxford University Press Country of Publication: England NLM ID: 100883649 Publication Model: Print Cited Medium: Print ISSN: 1099-5129 (Print) Linking ISSN: 10995129 NLM ISO Abbreviation: Europace Subsets: MEDLINE
Subject
Language
English
ISSN
1099-5129
Abstract
Tilt induced prolonged asystole has been considered to identify a distinct subgroup of patients with neurally mediated syncope and management including permanent pacemaker implantation has been suggested. To evaluate the reproducibility of asystolic response during head-up tilt testing (HUT), 33 patients with neurally mediated syncope and asystolic response (> or = 3 seconds) during HUT prospectively underwent two consecutive tests 13 +/- 15 days apart. On repeat tilt testing asystole was reproduced in 12 patients (36%), while 8 patients still had a positive HUT, but without asystole. Remarkably, 13 patients (40%) had a negative repeat HUT. Among 12 patients with asystole on both HUTs there was no significant difference in duration of asystole (14 371 +/- 11 430 ms vs 13 707 +/- 10 470 ms, P = ns) and time to syncope (36 +/- 20 min vs 37 +/- 20 min, P = ns) during initial and repeat HUTs. In conclusion, asystole during tilt testing does not seem to be a reproducible response.