학술논문
Psychological Status of the Participants in Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease Colombia.
Document Type
Academic Journal
Author
Ramos C; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; University of Antioquia, Medellin, Colombia.; Madrigal C; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Aguirre-Acevedo DC; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; University of Antioquia, Medellin, Colombia.; Giraldo-Chica M; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Acosta-Baena N; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Aponte C; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Aguillón D; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; University of Antioquia, Medellin, Colombia.; Gómez M; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Espinosa A; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Madrigal L; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Uribe C; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Saldarriaga A; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Alzate D; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Ruiz A; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Andrade A; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Lopez H; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Langbaum JB; Banner Alzheimer's Institute, Phoenix, AZ, USA.; Sink KM; Genentech Inc., South San Francisco, CA, USA.; Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA.; Tariot PN; Banner Alzheimer's Institute, Phoenix, AZ, USA.; Ríos-Romenets S; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; Lopera F; Neuroscience Group of Antioquia, University of Antioquia, Medellin, Colombia.; University of Antioquia, Medellin, Colombia.
Source
Publisher: IOS Press Country of Publication: Netherlands NLM ID: 9814863 Publication Model: Print Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Subject
Language
English
Abstract
Background: The SARS-CoV2 global pandemic impacted participants in the Alzheimer's Prevention Initiative (API) Autosomal Dominant Alzheimer's Disease (ADAD) clinical trial, who faced three stressors: 1) fear of developing dementia; 2) concerns about missing treatment; and 3) risk of SARS-CoV2 infection.
Objective: To describe the frequency of psychological disorders among the participants of the API ADAD Colombia clinical study, treated by a holistic mental health team during the COVID-19 pandemic. The extent of use of mental health team services was explored considering different risk factors, and users and non-users of these services were compared.
Methods: Participants had free and optional access to psychology and psychiatry services, outside of the study protocol. Descriptive statistics was used to analyze the frequency of the mental health difficulties. A multivariable logistic regression model has been used to assess associations with using this program.
Results: 66 participants were treated by the Mental Health Team from March 1, 2020, to December 31, 2020. Before and after the start of the pandemic, the most common psychological problems were anxiety (36.4% before, 63.6% after) and depression (34.8% before, 37.9% after). 70% of users assisted by psychology and 81.6% of those assisted by psychiatry felt that the services were useful for them. Female sex, depression, and anxiety before the pandemic were positively associated with being assisted by either psychology or psychiatry, while the association with hyperlipidemia was negative.
Conclusions: A holistic mental health program, carried out in the context of a study, could mitigate psychopathology during pandemics such as COVID-19.
Objective: To describe the frequency of psychological disorders among the participants of the API ADAD Colombia clinical study, treated by a holistic mental health team during the COVID-19 pandemic. The extent of use of mental health team services was explored considering different risk factors, and users and non-users of these services were compared.
Methods: Participants had free and optional access to psychology and psychiatry services, outside of the study protocol. Descriptive statistics was used to analyze the frequency of the mental health difficulties. A multivariable logistic regression model has been used to assess associations with using this program.
Results: 66 participants were treated by the Mental Health Team from March 1, 2020, to December 31, 2020. Before and after the start of the pandemic, the most common psychological problems were anxiety (36.4% before, 63.6% after) and depression (34.8% before, 37.9% after). 70% of users assisted by psychology and 81.6% of those assisted by psychiatry felt that the services were useful for them. Female sex, depression, and anxiety before the pandemic were positively associated with being assisted by either psychology or psychiatry, while the association with hyperlipidemia was negative.
Conclusions: A holistic mental health program, carried out in the context of a study, could mitigate psychopathology during pandemics such as COVID-19.